ID F2Y1H9_9PHYC Unreviewed; 986 AA.
AC F2Y1H9;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Early transcription factor 70 kDa subunit {ECO:0000256|ARBA:ARBA00017865};
DE AltName: Full=ATP-dependent helicase VETFS {ECO:0000256|ARBA:ARBA00032553};
GN ORFNames=162322600 {ECO:0000313|EMBL:ADX05972.1};
OS Organic Lake phycodnavirus 1.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Algavirales; Phycodnaviridae; environmental samples.
OX NCBI_TaxID=938081 {ECO:0000313|EMBL:ADX05972.1};
RN [1] {ECO:0000313|EMBL:ADX05972.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21444812; DOI=10.1073/pnas.1018221108;
RA Yau S., Lauro F.M., DeMaere M.Z., Brown M.V., Thomas T., Raftery M.J.,
RA Andrews-Pfannkoch C., Lewis M., Hoffman J.M., Gibson J.A., Cavicchioli R.;
RT "Virophage control of antarctic algal host-virus dynamics.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:6163-6168(2011).
CC -!- SIMILARITY: Belongs to the helicase family. VETF subfamily.
CC {ECO:0000256|ARBA:ARBA00008152}.
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DR EMBL; HQ704802; ADX05972.1; -; Genomic_DNA.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45766; DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45766:SF3; SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A-LIKE PROTEIN 1; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW ATP-binding {ECO:0000313|EMBL:ADX05972.1};
KW Helicase {ECO:0000313|EMBL:ADX05972.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000313|EMBL:ADX05972.1};
KW Transcription {ECO:0000256|ARBA:ARBA00023015};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 734..891
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 541..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 986 AA; 115822 MW; AEA5E971A3618DDB CRC64;
MNKIVSTELA YKNPEIGKIN DFIRVLNPRY NLFLNTLTSF YANKPILLGD SILLNEPEVR
EKKKSIIKER VVKSLKPAPL FVDVDNELLK DYDFYNPNIM TIEKKDFYLD RQYGFMDSVH
SLLEDLYKEE DGEDSCDKSS DFIMLKHQKI VQTYLNSYTP YRGLLLYHGL GSGKTCSSIG
ILEGMKHDKK IYIMTPASLQ ENYRTQMSFC GDKLFTTKHH WKKVKSNSDV VYQLFKQYLF
LDNDKELLEK YMTKYNNYVW LIHDDDTEPN YEMLNNEEKQ QIKELIRILI SMKYNFINYN
GLNKKSWEKL KSANKTNPFH NSVVVIDEAH NFISRVNNKK MTNKTSVSTD MYENIMDAQN
CKVVLLSGTP YINAPSELGI MINLVSGYTT EYEVILMKKY ETSILKEKLK PLSKYNMIDY
KFDRLYIVRN PYGFITTLNK EVQYEDMPLY NDTNFEELIR NTINVPIKQI NVHKYKRVPD
EEKEFNGLFV KKQDNLRVIN NKEFFQTRIS GLISYLGDKT SLMPRLEPMI TEKIPMSSHQ
RKEYELYKKR ESSSKKSDQK KDGSYKVFTR AACNFVFDED IKRPFPESNK VKTEADFDYI
EVTQRLKQAD GIEEDGDAIQ ENENYDTSIK NFMKSVRTNR NTLLFNNLRF FVSKPFEKPN
DDPEMGLIKY SPKFHSILEN IIKDVNTCQL LYSSFRRIEG IEMMRQLLKY QGFRELVVFK
NAAGNYDLKL EGIYSEDSYK ETRVFALYTG TEEKEVKEIV RNIYNSDLTK LSNTMNARLK
DVYKNDDLDN LHGSLINLLM ITSSGAEGID LQNVRYVHIT EPYWHNVRLE QVIGRARRIC
SHNRLPLEEQ NVQVYLYISS MKEELTKKEM STDEFLLKIM EEKKVLSESF LNTLKESAID
CMPSKTNKCF KFPSNKNKEK FSYALDYKKE PIQQKVKDDQ FVDQELLYNG ILTKVKVDTR
KKPNKVYIEE NGKLKDIGIL QGNQIV
//
