ID F2Y5J1_GRAGR Unreviewed; 216 AA.
AC F2Y5J1;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 22-FEB-2023, entry version 31.
DE SubName: Full=Glutamate receptor metabotropic 8 {ECO:0000313|EMBL:ADZ57735.1};
DE Flags: Fragment;
GN Name=GRM8 {ECO:0000313|EMBL:ADZ57735.1};
OS Grampus griseus (Risso's dolphin) (Delphinus griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Grampus.
OX NCBI_TaxID=83653 {ECO:0000313|EMBL:ADZ57735.1};
RN [1] {ECO:0000313|EMBL:ADZ57735.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21315162; DOI=10.1016/j.ympev.2011.02.009;
RA Zhou X., Xu S., Yang Y., Zhou K., Yang G.;
RT "Phylogenomic analyses and improved resolution of Cetartiodactyla.";
RL Mol. Phylogenet. Evol. 61:255-264(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HQ825764; ADZ57735.1; -; Genomic_DNA.
DR AlphaFoldDB; F2Y5J1; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR017978; GPCR_3_C.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR24060:SF26; METABOTROPIC GLUTAMATE RECEPTOR 8; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:ADZ57735.1};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..216
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADZ57735.1"
FT NON_TER 216
FT /evidence="ECO:0000313|EMBL:ADZ57735.1"
SQ SEQUENCE 216 AA; 24074 MW; 5D60CD5C2190BA87 CRC64;
QRPNINRTGC QLIPIIKLEW HSPWAVVPVF VAILGIIATT FVIVTFVRYN DTPIVRASGR
ELSYVLLTGI FLCYSITFLM IAAPDTVICS FRRIFLGLGM CFSYAALLTK TNRIHRIFEQ
GKKSVTAPKF ISPASQLVIT FSLISIQLLG VCVWFVVDPP HIIIDYGEQR TLDPENARGV
LKCDISDLSL ICSLGYSILL MVTCTVYAIK TRGVPE
//
