ID F2ZBT4_CUCEC Unreviewed; 460 AA.
AC F2ZBT4;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Hemolytic lectin-S1 {ECO:0000313|EMBL:BAK19472.1};
GN Name=lecS1 {ECO:0000313|EMBL:BAK19472.1};
OS Cucumaria echinata (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Dendrochirotacea; Dendrochirotida; Cucumariidae; Cucumaria.
OX NCBI_TaxID=40245 {ECO:0000313|EMBL:BAK19472.1};
RN [1] {ECO:0000313|EMBL:BAK19472.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=22313748; DOI=10.1271/bbb.110635;
RA Shimizu Y., Yamazaki H., Yoshida S., Yonekura M., Kouzuma Y.;
RT "Molecular cloning, functional expression, and characterization of
RT isolectin genes of hemolytic lectin CEL-III from the marine invertebrate
RT Cucumaria echinata.";
RL Biosci. Biotechnol. Biochem. 76:276-282(2012).
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DR EMBL; AB626733; BAK19472.1; -; mRNA.
DR AlphaFoldDB; F2ZBT4; -.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR CDD; cd20214; PFM_CEL-III-like; 1.
DR CDD; cd00161; RICIN; 2.
DR Gene3D; 2.80.10.50; -; 2.
DR Gene3D; 3.30.1750.10; Hemolytic lectin CEL-III, C-terminal domain; 1.
DR InterPro; IPR028988; CEL-III_C_sf.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR11675; N-ACETYLGALACTOSAMINYLTRANSFERASE; 1.
DR PANTHER; PTHR11675:SF126; RIBOSOME-INACTIVATING PROTEIN; 1.
DR Pfam; PF00652; Ricin_B_lectin; 2.
DR SMART; SM00458; RICIN; 2.
DR SUPFAM; SSF111265; Hemolytic lectin CEL-III, C-terminal domain; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 2.
DR PROSITE; PS50231; RICIN_B_LECTIN; 3.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Lectin {ECO:0000256|ARBA:ARBA00022734, ECO:0000313|EMBL:BAK19472.1};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..460
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003293806"
FT DOMAIN 38..175
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|SMART:SM00458"
FT DOMAIN 177..310
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|SMART:SM00458"
SQ SEQUENCE 460 AA; 50766 MW; 18B43B4EE7EBA6B5 CRC64;
MEHMRVLFSL SKTLCFFFMV SLVPCGFAQV LCTNPLDIGE LRNYKSKQCV DIVGNQGSGN
IATHDCDGLS DQQIIMCGDG TIRNEARNYC FTPDGSGNAN VMSSSCTLYP EIPSSQRWRL
GRKKTFTDNG GIEQVATEII NLASGKCLDV EGSDGTGDIG VYDCQNLDDQ YFYIRSRGPE
LFYGRLRNEK SDLCLDVEGS EGKGNVLMYS CEDNLDQWFR YYENGEIVNE KSGMCLDVEG
RDGSGNVGIY RCDDLRDQMW SRPNAYCNGD HCSFLNKESN KCLDVSGDQG TGDVGTWQCD
GLPDQRFKWV FDDWEVPTAT WNMVGCNQNG KVSQQISNTI SFSSTVTAGV AVEVSSTIEK
GVIFAKAEVG VKVSASLSKA WTNSQSGTTA ITYTCDNYDS DEEFTRGCMW QLAIETTEVK
SGDLLVWDPQ IIKCTRSNTA PKCAPFTKCA NEDCTFCTGI
//
