ID F2ZC49_9ENTO Unreviewed; 130 AA.
AC F2ZC49;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Genome polyprotein {ECO:0000256|ARBA:ARBA00020107};
DE Flags: Fragment;
OS Rhinovirus C.
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Picornavirales; Picornaviridae; Ensavirinae; Enterovirus.
OX NCBI_TaxID=463676 {ECO:0000313|EMBL:BAK22585.1};
RN [1] {ECO:0000313|EMBL:BAK22585.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HRV/Yamaguchi/2010/YU64 {ECO:0000313|EMBL:BAK22585.1};
RA Arakawa M., Okamoto-Nakagawa R., Toda S., Tsukagoshi H., Kobayashi M.,
RA Ryo A., Mizuta K., Hasegawa S., Hirano R., Wakiguchi H., Kudo K.,
RA Tanaka R., Morita Y., Noda M., Kozawa K., Ichiyama T., Shirabe K.,
RA Kimura H.;
RT "Molecular epidemiological study of human rhinovirus species A, B and C
RT from patients with acute respiratory illnesses in Japan.";
RL J. Med. Microbiol. 61:410-419(2012).
CC -!- FUNCTION: Component of immature procapsids, which is cleaved into
CC capsid proteins VP4 and VP2 after maturation (By similarity). Allows
CC the capsid to remain inactive before the maturation step.
CC {ECO:0000256|ARBA:ARBA00025202}.
CC -!- SUBUNIT: Interacts with capsid protein VP1 and capsid protein VP3 to
CC form heterotrimeric protomers. {ECO:0000256|ARBA:ARBA00011474}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Host
CC cytoplasm {ECO:0000256|ARBA:ARBA00004192}. Virion
CC {ECO:0000256|ARBA:ARBA00004328}.
CC -!- SIMILARITY: Belongs to the picornaviruses polyprotein family.
CC {ECO:0000256|ARBA:ARBA00008303}.
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DR EMBL; AB628135; BAK22585.1; -; Genomic_RNA.
DR GO; GO:0019028; C:viral capsid; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0044694; P:pore-mediated entry of viral genome into host cell; IEA:UniProtKB-KW.
DR GO; GO:0039657; P:suppression by virus of host gene expression; IEA:UniProtKB-KW.
DR GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.20; -; 1.
DR Gene3D; 4.10.80.10; Picornavirus coat protein VP4; 1.
DR InterPro; IPR003138; Pico_P1A.
DR InterPro; IPR036988; Pico_P1A_sf.
DR InterPro; IPR001676; Picornavirus_capsid.
DR InterPro; IPR029053; Viral_coat.
DR Pfam; PF02226; Pico_P1A; 1.
DR Pfam; PF00073; Rhv; 1.
DR SUPFAM; SSF88633; Positive stranded ssRNA viruses; 1.
PE 3: Inferred from homology;
KW Capsid protein {ECO:0000256|ARBA:ARBA00022561};
KW Eukaryotic host gene expression shutoff by virus
KW {ECO:0000256|ARBA:ARBA00023247};
KW Eukaryotic host translation shutoff by virus
KW {ECO:0000256|ARBA:ARBA00022809};
KW Host gene expression shutoff by virus {ECO:0000256|ARBA:ARBA00022995};
KW Host-virus interaction {ECO:0000256|ARBA:ARBA00022581};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Myristate {ECO:0000256|ARBA:ARBA00022707};
KW Pore-mediated penetration of viral genome into host cell
KW {ECO:0000256|ARBA:ARBA00023255};
KW Viral attachment to host cell {ECO:0000256|ARBA:ARBA00022804};
KW Viral penetration into host cytoplasm {ECO:0000256|ARBA:ARBA00022595};
KW Virion {ECO:0000256|ARBA:ARBA00022561};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 91..130
FT /note="Picornavirus capsid"
FT /evidence="ECO:0000259|Pfam:PF00073"
FT NON_TER 130
FT /evidence="ECO:0000313|EMBL:BAK22585.1"
SQ SEQUENCE 130 AA; 14011 MW; 477E152F39303977 CRC64;
MGAQVSRQSV GSHETMIHAG TGAVVKYFNV NYYKDAASSG LTKQDFSQDP SKFTQPVADL
LTNPALMSPS IEACGFSDRL KQITIGNSTI TTQDAVNSIV AYGEWPSYLS DIDATSVDKP
THPETSSDRF
//
