ID   F3AAA9_9FIRM            Unreviewed;       261 AA.
AC   F3AAA9;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=Pterin-binding domain-containing protein {ECO:0000259|PROSITE:PS50972};
GN   ORFNames=HMPREF0992_00004 {ECO:0000313|EMBL:EGG85077.1};
OS   Lachnospiraceae bacterium 6_1_63FAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=658083 {ECO:0000313|EMBL:EGG85077.1, ECO:0000313|Proteomes:UP000004368};
RN   [1] {ECO:0000313|EMBL:EGG85077.1, ECO:0000313|Proteomes:UP000004368}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=6_1_63FAA {ECO:0000313|EMBL:EGG85077.1,
RC   ECO:0000313|Proteomes:UP000004368};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Ambrose C., Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., White J.,
RA   Yandava C., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 6_1_63FAA.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the vitamin-B12 dependent methionine synthase
CC       family. {ECO:0000256|ARBA:ARBA00010398}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGG85077.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ACTV01000001; EGG85077.1; -; Genomic_DNA.
DR   AlphaFoldDB; F3AAA9; -.
DR   HOGENOM; CLU_070996_0_0_9; -.
DR   OrthoDB; 9775133at2; -.
DR   Proteomes; UP000004368; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0042558; P:pteridine-containing compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.20; Dihydropteroate synthase-like; 1.
DR   InterPro; IPR011005; Dihydropteroate_synth-like_sf.
DR   InterPro; IPR000489; Pterin-binding_dom.
DR   NCBIfam; NF040758; CODH_ACS_meth; 1.
DR   PANTHER; PTHR45833:SF2; BIFUNCTIONAL HOMOCYSTEINE S-METHYLTRANSFERASE_5,10-METHYLENETETRAHYDROFOLATE REDUCTASE; 1.
DR   PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR   Pfam; PF00809; Pterin_bind; 1.
DR   SUPFAM; SSF51717; Dihydropteroate synthetase-like; 1.
DR   PROSITE; PS50972; PTERIN_BINDING; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          4..249
FT                   /note="Pterin-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50972"
SQ   SEQUENCE   261 AA;  28618 MW;  4BF9F1888D84109D CRC64;
     MAKFVTIGER IHCISPVIRK AMAERDPEPI LKRAKEQLDA GATYLDVNIG PAENDGEDLM
     KWAVQLLQSN FDNVPLALDT ANKKAIEAGI SVYNRSKGKP IVNSADAGGR IENIDLAAAN
     DAIVIALCSA EGIAADNDER MMHCQNMLER GMMLGMEPTD LWFDPLFLVV KGMQDKQMEV
     LEAIKMFSEM GLNSTGGLSN NSNGMPKHIR PIMDSALVAM CMMQGLTSAI VNPCDLRLME
     TIKSCDVFKN NTLYADSYLE L
//