ID F3AHM8_9FIRM Unreviewed; 578 AA.
AC F3AHM8;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=Signal transduction histidine kinase internal region domain-containing protein {ECO:0000259|Pfam:PF06580};
GN ORFNames=HMPREF0992_02573 {ECO:0000313|EMBL:EGG80693.1};
OS Lachnospiraceae bacterium 6_1_63FAA.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=658083 {ECO:0000313|EMBL:EGG80693.1, ECO:0000313|Proteomes:UP000004368};
RN [1] {ECO:0000313|EMBL:EGG80693.1, ECO:0000313|Proteomes:UP000004368}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=6_1_63FAA {ECO:0000313|EMBL:EGG80693.1,
RC ECO:0000313|Proteomes:UP000004368};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Ambrose C., Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., White J.,
RA Yandava C., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 6_1_63FAA.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG80693.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ACTV01000028; EGG80693.1; -; Genomic_DNA.
DR AlphaFoldDB; F3AHM8; -.
DR HOGENOM; CLU_020473_6_0_9; -.
DR OrthoDB; 138378at2; -.
DR Proteomes; UP000004368; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 375..453
FT /note="Signal transduction histidine kinase internal
FT region"
FT /evidence="ECO:0000259|Pfam:PF06580"
SQ SEQUENCE 578 AA; 66679 MW; 458A995332BCDDF6 CRC64;
MKEKLQKFFE KFTIKKKIVI ACIPFLLISY IILFLSVTLI MYYQMKNMVF EQTKQNIREK
TRLINQKLDN YDKITTNYLY YTSDVQTYLN LNQNDMTPDE LEDWKRTITS YTNSLLTDNN
PEIEKVKLFN KYGNLYINST IYANTLELTR KHAKSIHEIA QNCHGKIVIK KNPEQSQMLT
IARTVHIPTL DASNEEIGFL LLDISKSALK KQLAIQENED AMYILLVDDE GEILVNASSR
TDEECLRILS RNKDNSYIIN RKNLAYGGCQ IISILNQSVL FADVYKLFKL EVGIMIISVL
IILGAIIYSG NIISGQVSRF INKLNQTQEI NQNAYMRVDS KDEFQDLAKV YNNMLARIDK
LIHTVYIKEL LIKDAQLESL QAQINPHFLY NTLDCVNSLV DMGEKESVKK VVTSLASIMR
MSIKGNTFIS VREDISYIEQ YVFIQRMRFQ NKILFLIEVP ESMYLYYIPK LTIQPLVENA
VLHGVANLKE TGMIGIFGSE DENNIYISIK DNGFGMPEEI IKAFDKLEDF KGNNKSHIGI
FNIQKKLQIL YGSDYGLTIE PVRPHGTLLM CDKEVVEV
//
