ID   F3L1N5_9GAMM            Unreviewed;       581 AA.
AC   F3L1N5;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=Cell division protein FtsI (Peptidoglycan synthetase) {ECO:0000313|EMBL:EGG29738.1};
DE   SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:QHJ88735.1};
GN   ORFNames=EYZ66_10735 {ECO:0000313|EMBL:QHJ88735.1}, IMCC3088_1375
GN   {ECO:0000313|EMBL:EGG29738.1};
OS   Aequoribacter fuscus.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae;
OC   Aequoribacter.
OX   NCBI_TaxID=2518989 {ECO:0000313|EMBL:EGG29738.1, ECO:0000313|Proteomes:UP000005615};
RN   [1] {ECO:0000313|EMBL:EGG29738.1, ECO:0000313|Proteomes:UP000005615}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IMCC3088 {ECO:0000313|EMBL:EGG29738.1,
RC   ECO:0000313|Proteomes:UP000005615};
RX   PubMed=21551310; DOI=10.1128/JB.05111-11;
RA   Jang Y., Oh H.M., Kang I., Lee K., Yang S.J., Cho J.C.;
RT   "Genome sequence of strain IMCC3088, a proteorhodopsin-containing marine
RT   bacterium belonging to the OM60/NOR5 clade.";
RL   J. Bacteriol. 193:3415-3416(2011).
RN   [2] {ECO:0000313|EMBL:QHJ88735.1, ECO:0000313|Proteomes:UP000464557}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IMCC3088 {ECO:0000313|EMBL:QHJ88735.1,
RC   ECO:0000313|Proteomes:UP000464557};
RA   Li S.-H.;
RT   "Halieaceae_genomes.";
RL   Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AEIG01000034; EGG29738.1; -; Genomic_DNA.
DR   EMBL; CP036423; QHJ88735.1; -; Genomic_DNA.
DR   RefSeq; WP_009575670.1; NZ_CP036423.1.
DR   AlphaFoldDB; F3L1N5; -.
DR   STRING; 2518989.IMCC3088_1375; -.
DR   KEGG; afus:EYZ66_10735; -.
DR   eggNOG; COG0768; Bacteria.
DR   OrthoDB; 9789078at2; -.
DR   Proteomes; UP000005615; Unassembled WGS sequence.
DR   Proteomes; UP000464557; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.450.330; -; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   4: Predicted;
KW   Carboxypeptidase {ECO:0000256|ARBA:ARBA00022645};
KW   Cell cycle {ECO:0000313|EMBL:EGG29738.1};
KW   Cell division {ECO:0000313|EMBL:EGG29738.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022645};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Protease {ECO:0000256|ARBA:ARBA00022645};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005615};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          62..207
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          250..546
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   581 AA;  61721 MW;  83279E0F9D5644B5 CRC64;
     MSRVAGEVQA GSWRFLLCLA FLLILAVALI GRLAMLQLLD VEQGQQFLQS QGDARTVRYA
     QIPAHRGAIL DRNGQLLAVS TPVLTLSLNP QQFDVSNLDT LARLLALDVK ELKHRFQQYQ
     DRQFMYVKKH VTPEQAAPVL ASGMPGLVAQ RDYKRFYPAA DLTAQLIGLT GDSDTGLSGL
     ELAFDHVLSG TPGRKKYIKD RSGKAIRDVG IESTAADGRD VRLSIDLRLQ YVQYRALQSV
     VAKSEAMGAS AITIDSHTGE ILAVSNYPSF NPNDRSTFSA SAARNRVFVD QYEPGSTLKA
     LTAVAALETG RYSADTVFNT SPGWMVVQGK TFKDPVDYGQ LTLAGVLAKS SQIGTTQLAL
     DIGRDSLLPV LQRFGVGQPL GIGFPGETAG LLPQQSRWSD IEQATLAFGY GVTVSPAQLA
     AFYGAIANSG RLQPLTLVAT AKANRPPAMP VTTPAIASEL RDMLGTVTAK GGTGILANVP
     GFSVAGKTGT VHKAGAGGYD RKRYIAWFAG MAPAENPRFV TVVMVNEPKG ESVGGGAIAA
     PVFADMTAAM LRILGEAPNQ QSPVIQLAAA RQSVAGESSD G
//