ID F3MAC6_9BACL Unreviewed; 333 AA.
AC F3MAC6;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=4-hydroxythreonine-4-phosphate dehydrogenase {ECO:0000313|EMBL:EGG35681.1};
DE EC=1.1.1.262 {ECO:0000313|EMBL:EGG35681.1};
GN Name=pdxA {ECO:0000313|EMBL:EGG35681.1};
GN ORFNames=HMPREF9412_0127 {ECO:0000313|EMBL:EGG35681.1};
OS Paenibacillus sp. HGF5.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=908341 {ECO:0000313|EMBL:EGG35681.1, ECO:0000313|Proteomes:UP000004272};
RN [1] {ECO:0000313|EMBL:EGG35681.1, ECO:0000313|Proteomes:UP000004272}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HGF5 {ECO:0000313|EMBL:EGG35681.1,
RC ECO:0000313|Proteomes:UP000004272};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC Evidence={ECO:0000256|ARBA:ARBA00001968};
CC -!- SIMILARITY: Belongs to the PdxA family. PdxA2 subfamily.
CC {ECO:0000256|ARBA:ARBA00009464}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG35681.1}.
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DR EMBL; AEXS01000092; EGG35681.1; -; Genomic_DNA.
DR RefSeq; WP_009592407.1; NZ_AEXS01000092.1.
DR AlphaFoldDB; F3MAC6; -.
DR OrthoDB; 9801783at2; -.
DR Proteomes; UP000004272; Unassembled WGS sequence.
DR GO; GO:0050570; F:4-hydroxythreonine-4-phosphate dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR005255; PdxA_fam.
DR NCBIfam; TIGR00557; pdxA; 1.
DR PANTHER; PTHR30004; 4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR30004:SF6; D-THREONATE 4-PHOSPHATE DEHYDROGENASE; 1.
DR Pfam; PF04166; PdxA; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EGG35681.1}.
SQ SEQUENCE 333 AA; 35713 MW; 8FB80EF24EB0BA4B CRC64;
MKPTVGITMG DAAGIGPEII MKALSHREMY DNCNPLVIGD AKILERVLPI IGSSLKVNAI
QEPAEAKYEF GTVDVIDLDL VPADLAFGEV SAVAGDAAFQ FLARAIDLAK QRKIHSICTA
PLNKEALHQG GHMYPGHTEI LADLTDTKDF SMMLTTPNLR VIHLTTHMGL IEAIQSINPE
RTYTVVKLAH DTLKKAGFDN PRVAVCGINP HAGENGLFGN GEEEEKLLPG IKRAQQEGIN
VVGPLPADTL FFRAGRGDFD IVVACYHDQG HAPIKVMGIE EGVNITVGLK GGIIRTSVDH
GTAFDIAGKN IADDKSMLAA IRSAIELAPK DQM
//
