ID   F3ND64_9ACTN            Unreviewed;      1345 AA.
AC   F3ND64;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Putative ATP/GTP-binding protein {ECO:0000313|EMBL:EGG48647.1};
GN   ORFNames=SGM_1078 {ECO:0000313|EMBL:EGG48647.1};
OS   Streptomyces griseoaurantiacus M045.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX   NCBI_TaxID=996637 {ECO:0000313|EMBL:EGG48647.1, ECO:0000313|Proteomes:UP000003022};
RN   [1] {ECO:0000313|EMBL:EGG48647.1, ECO:0000313|Proteomes:UP000003022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M045 {ECO:0000313|EMBL:EGG48647.1,
RC   ECO:0000313|Proteomes:UP000003022};
RX   PubMed=21551298; DOI=10.1128/JB.05053-11;
RA   Li F., Jiang P., Zheng H., Wang S., Zhao G., Qin S., Liu Z.;
RT   "Draft genome sequence of the marine bacterium Streptomyces
RT   griseoaurantiacus M045, which produces novel manumycin-type antibiotics
RT   with a pABA core component.";
RL   J. Bacteriol. 193:3417-3418(2011).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGG48647.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AEYX01000020; EGG48647.1; -; Genomic_DNA.
DR   RefSeq; WP_006138610.1; NZ_AEYX01000020.1.
DR   STRING; 996637.SGM_1078; -.
DR   eggNOG; COG0455; Bacteria.
DR   eggNOG; COG0457; Bacteria.
DR   Proteomes; UP000003022; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   NCBIfam; NF040586; FxSxx_TPR; 1.
DR   PANTHER; PTHR46082:SF6; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR46082; ATP/GTP-BINDING PROTEIN-RELATED; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   Pfam; PF13374; TPR_10; 3.
DR   Pfam; PF13424; TPR_12; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   SUPFAM; SSF48452; TPR-like; 4.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000003022}.
FT   DOMAIN          355..466
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|Pfam:PF13676"
SQ   SEQUENCE   1345 AA;  149645 MW;  E0CD128A9635ACCC CRC64;
     MTGDEGRIIT FYSYKGGTGR TMALANTAWI LASAGHRVLA VDWDLDAPGL DRFLHPFLDE
     EKLRTTPGVL ELVSRFSESL TRVRHTTAAE AYGEGHGSVE TVTLPGGEWG AEMLPLDSCV
     LPVSWHFPAG GWLDYLPAGT KNKGYLTAFS QFDWKPFMDG PLATRFLERL KREFGDRYDY
     VLVDSRTGLN DISDICTVNL PHVLVTCFTP SSQSIDGAVA VAERIEEMHR DRRIRILPVP
     MRVENAEADR LEAARGQFQY RFDRILRRHL APGTEPDDYW GRVEIPYRPI YSYEETLAPF
     REAPGDPKSL LAAYERLAEV LSDGRVTRMA RIDEGLRRRT LERYTRHRPP RVSDVYISFV
     PQDRSWAMWA GAVLEDAGFK VHLAQEGTAE GGRHRQEIER VVESAPHTLV VLSEAYLRSS
     RFRTTWEAVY AAGGMDEDRR LVSMSVERLS LGSPFTDRLA DLTRCDTGEA ARDTLLACFG
     RTFAPASRAH YTGGERRMPR YPGAEPPVWS VPLRTASFTG RTSLLERIRE RLCEGDGRAL
     LLKGLGGVGK TLLAREFAHR YKSDYDIAWH IQAEQRNLAV EQFAAMAGPL GVAERKNPTD
     TAKAVREALD RGEPYGSWLL ILDNAVEAGN LPDFMVTGRS GHVLITSQRS EGWGRWADTL
     EVGVFEREES ITHLRGRLPD CGRADADQIA EALGDLPIAV EQAAAGIEQS KVGARAYLRE
     LQAPATGAAR TRGSGEDKAG DVTRVSGATW EFALGQLRRK FPQAVQLLQI CAYFGPEPIS
     MDLLEGAEVS RALGDSRTVA RAYQELSRFS LVTVDRKIWG VQVHRLVQRA MRESMTEQER
     QAARDVVYRT LIAARPSKDD PEDPNTWESY RVIWSHLGTP WALGATEGGI RELLVDRVRQ
     LRRRGELAQA MELSTRCVTT WTENGPPDDR WTLHMRFQIA NILRAQGRYE ESLALDEEVR
     ARQLATLPDD DQHVLMTTSS IAADLRGLGR LSEALDHDRR THRRYAEIYG EDHPRTLGAA
     NNLAVSLRLS GDYYGARALD SRTLALREEI LLHDHPLTIE SAVNLGRDHR DCGDYAASVS
     LLRRAYDRCL QNPRLTQGSP TVLNTAKGLA GALRRTGRPA EAQELVEHVL KHGPEGEKGA
     SPERLLVEMS LAGDLAAQDR RDEGLRLIRR VLDDLRDSLG EDHPQTVACS ANYAVLLLGD
     IDTAAHPPAG DTATVEEAAR ARTLLLRALE AFTELSGEHH PYTLVCRVNL AAADAALGDR
     EEARRGCQEA YDLLREALEP THPSTLTCAG NLGLILGLLG RPQEARSTLQ AALSALAKRL
     GEDHPRVRAL REERITCLEL EPSPI
//