ID F3NKM3_9ACTN Unreviewed; 1335 AA.
AC F3NKM3;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=ATP-dependent helicase {ECO:0000313|EMBL:EGG46182.1};
GN ORFNames=SGM_3687 {ECO:0000313|EMBL:EGG46182.1};
OS Streptomyces griseoaurantiacus M045.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=996637 {ECO:0000313|EMBL:EGG46182.1, ECO:0000313|Proteomes:UP000003022};
RN [1] {ECO:0000313|EMBL:EGG46182.1, ECO:0000313|Proteomes:UP000003022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M045 {ECO:0000313|EMBL:EGG46182.1,
RC ECO:0000313|Proteomes:UP000003022};
RX PubMed=21551298; DOI=10.1128/JB.05053-11;
RA Li F., Jiang P., Zheng H., Wang S., Zhao G., Qin S., Liu Z.;
RT "Draft genome sequence of the marine bacterium Streptomyces
RT griseoaurantiacus M045, which produces novel manumycin-type antibiotics
RT with a pABA core component.";
RL J. Bacteriol. 193:3417-3418(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG46182.1}.
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DR EMBL; AEYX01000038; EGG46182.1; -; Genomic_DNA.
DR RefSeq; WP_006141452.1; NZ_AEYX01000038.1.
DR STRING; 996637.SGM_3687; -.
DR eggNOG; COG1643; Bacteria.
DR Proteomes; UP000003022; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd17989; DEXHc_HrpA; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:EGG46182.1};
KW Hydrolase {ECO:0000313|EMBL:EGG46182.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000003022}.
FT DOMAIN 87..251
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 279..446
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 643..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1335 AA; 151397 MW; 5724ECC190932738 CRC64;
MSTHPAPALG ALAPRLTELS LRDAHRLGRR LEGARKIRKP EARAAVLAEI EGEVARAEER
MAARRARVPV VTYPEQLPVS QKKDEIAEAI RDHQVVIVAG ETGSGKTTQI PKICMELGRG
VRGMIGHTQP RRIAARTVAE RVAEELDTPL GETVGWKVRF TDQVDPEATF VKLMTDGILL
AEIQTDRELR AYDTIIIDEA HERSLNIDFL LGYLAQLLPK RPDLKVVITS ATIDPERFSR
HFGDAPIVEV SGRTYPVEVR YRPLLEEDSD EADRDQITAI TDAVEELMAE GPGDILVFLS
GEREIRDTAD ALEKKKYRST EVLPLYARLS HAEQHRVFQQ HSGRRIVLAT NVAETSLTVP
GIKYVIDPGF ARISRYSHRT KVQRLPIEPV SQASANQRKG RCGRTSDGIC IRLYSEDDFL
TRPEFTDAEI LRTNLASVIL QMTAAGLGDI EKFPFIDPPD HRNIRDGVQL LQELGALDPA
QKDVRKRLTE TGRKLAQLPV DPRLARMVLE ADRNGCAREV MVIAAALSIQ DPRERPSEKQ
TQADQQHARF RDETSDFLAF LNLWRYIREQ QKERGSSSFR RMCKQEFLNF LRIREWQDIY
TQLRTVAKQM GIRLNEQDAP EDRIHVSLLA GLLSHIGMKD VKESKDSSGA AGTSGPGGRK
DGGRNEYVGA RNAKFAIFPG SALFKKPPRF VMSAELVETS RLWARVNARI EPEWVEPLAG
HLLKHTYSEP HWEKDQAAVM AYEKVTLYGV PIVAQRKINY GRVDAEVSRE LFIRNALVEG
DWRTHHKFFA DNRKLLSEVE ELEHRARRRD IVVDDETLFD FYEQRIPEHV VSGAHFDSWW
KHKRHEQPDF LDFEREMLIR ESAQEVTKAD YPDSWRQGPL KFRVTYQFEP GADADGVTVH
IPLQVLNQVT DEGFDWQIPG LREEVVTELI RSLPKPIRRN YVPAPNYARA FLERAVPLQE
PLTTTMAREL KRMVGVPFEA EDFDWGRVPD HLRITFRIVD ERRRKLAEDK DLQALKLRLK
PKARKALSQA AAATAERQGG ESVERAGLTD WTIGTLSRVF ETRRAGQPVK AYPALVDDGP
KADTVSVRLF DTEAEQTEAM WKGTRRLILR NIPVNPAKFA SDKLTNAQKL ALSANPHGSV
QALFEDCATA AADRLIADFG GPAWDEESYR KLYDKVRAEI VDTTVRTVGQ VQQVLAAWQA
CERRLKAVRS PALLPNLADV RAQLDALVRP GFVTEAGLRR LPDLMRYLIA ADRRLQQMPT
NVQRDTTRME KVHEMRDEYA WLREQLPAGR PVPAAVTEIR WMIEELRVSY FAHALGTAYP
VSDKRIVKAI DAAAP
//
