ID F3NQT8_9ACTN Unreviewed; 336 AA.
AC F3NQT8;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Exonuclease {ECO:0000313|EMBL:EGG43922.1};
GN ORFNames=SGM_5502 {ECO:0000313|EMBL:EGG43922.1};
OS Streptomyces griseoaurantiacus M045.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=996637 {ECO:0000313|EMBL:EGG43922.1, ECO:0000313|Proteomes:UP000003022};
RN [1] {ECO:0000313|EMBL:EGG43922.1, ECO:0000313|Proteomes:UP000003022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M045 {ECO:0000313|EMBL:EGG43922.1,
RC ECO:0000313|Proteomes:UP000003022};
RX PubMed=21551298; DOI=10.1128/JB.05053-11;
RA Li F., Jiang P., Zheng H., Wang S., Zhao G., Qin S., Liu Z.;
RT "Draft genome sequence of the marine bacterium Streptomyces
RT griseoaurantiacus M045, which produces novel manumycin-type antibiotics
RT with a pABA core component.";
RL J. Bacteriol. 193:3417-3418(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG43922.1}.
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DR EMBL; AEYX01000044; EGG43922.1; -; Genomic_DNA.
DR RefSeq; WP_006143364.1; NZ_AEYX01000044.1.
DR AlphaFoldDB; F3NQT8; -.
DR STRING; 996637.SGM_5502; -.
DR eggNOG; COG0847; Bacteria.
DR Proteomes; UP000003022; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd06127; DEDDh; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR006054; DnaQ.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR NCBIfam; TIGR00573; dnaq; 1.
DR PANTHER; PTHR30231; DNA POLYMERASE III SUBUNIT EPSILON; 1.
DR PANTHER; PTHR30231:SF4; PROTEIN NEN2; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00292; BRCT; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Exonuclease {ECO:0000313|EMBL:EGG43922.1};
KW Hydrolase {ECO:0000313|EMBL:EGG43922.1};
KW Nuclease {ECO:0000313|EMBL:EGG43922.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003022}.
FT DOMAIN 21..185
FT /note="Exonuclease"
FT /evidence="ECO:0000259|SMART:SM00479"
FT DOMAIN 243..321
FT /note="BRCT"
FT /evidence="ECO:0000259|SMART:SM00292"
FT REGION 206..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 336 AA; 36550 MW; 41656469C7EACF92 CRC64;
MLEDPTIAAP PASWPAAYPQ GYAVVDVETT GLARDDRIIS AAVYRLDARG EVEDHWYTTV
NPERDPGPVW IHGLTSEALE GAPLFHEVAG EFAARLTGRV LVAHNAVFDW SMIAREYARA
GQEPPVRQRL CTIALSKALA LPLPNHKLET LAAHFGVVQR RAHHALDDAR VLAEAFRPSL
HAAARDNVRL PLLECLPLTE WSATPRIGRQ ATPPGASRPG SWRQSRKLPP CPYPNPGRYE
EGRPLKQGMR VAFSGDTSVD RELLEDRAVD AGLHVATSLS RLTSLLVTND PDSGTSKVLK
ARQFGTPVVD EAAFGQLLQN VEPAAETEGA KGSKRA
//
