ID F3PD03_9ACTO Unreviewed; 866 AA.
AC F3PD03;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Negative regulator of genetic competence ClpC/MecB {ECO:0000313|EMBL:EGF50013.1};
GN ORFNames=HMPREF9056_02967 {ECO:0000313|EMBL:EGF50013.1};
OS Actinomyces sp. oral taxon 170 str. F0386.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=762963 {ECO:0000313|EMBL:EGF50013.1, ECO:0000313|Proteomes:UP000004404};
RN [1] {ECO:0000313|EMBL:EGF50013.1, ECO:0000313|Proteomes:UP000004404}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0386 {ECO:0000313|EMBL:EGF50013.1,
RC ECO:0000313|Proteomes:UP000004404};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGF50013.1}.
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DR EMBL; AFBL01000092; EGF50013.1; -; Genomic_DNA.
DR RefSeq; WP_009747114.1; NZ_GL882573.1.
DR AlphaFoldDB; F3PD03; -.
DR STRING; 762963.HMPREF9056_02967; -.
DR eggNOG; COG0542; Bacteria.
DR HOGENOM; CLU_005070_4_1_11; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000004404; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS50151; UVR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 2..144
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 421..456
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT REGION 830..866
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 866 AA; 95054 MW; E18E26A0EE0D394F CRC64;
MFERFTDRAR RVVVLAQDEA RALNHNYIGT EHLLLGLIHE GEGVAAKALE SMDISLDAVR
SQVIEIIGEG QSAPTGHIPF TPRGKKVFEL SMREALQLGH NYIGTEHLLL GLLREGEGVA
AQVLTNLGGD LSSVRQTVMQ MLSGYEGKET VNAGGPSKEG TPSGSAILDQ FGRNLTAAAR
EGKLDPVIGR KKEMERVMQV LSRRTKNNPV LIGEPGVGKT AVVEGLSQAI VHGDVPETLR
DKQLYSLDMG SLVAGSRYRG DFEERLKKVL KEVRTRGDIV LFIDEIHTLV GAGAAEGAVD
AASILKPMLA RGELQTIGAT TLEEYRKIEK DAALERRFQP VTVDQPSIEE TIGILTGLRD
RYEAFHRIVI TDEAIEAAAK LADRYINDRF LPDKAIDLVD EAGARLRIRR MTAPPELREI
DEKIAEVKRE KESAIDDQDF ERAASLRDDE RRLADERAAK EKAWKSGDLD QVAEVDEALI
AEVLAMSTGI PVVKLTEAES AKLLNMETEL HKRIIGQNKA IEALSKSIRR TRAGLKDPKR
PGGSFIFAGP TGVGKTELAK ALAEFLFDDE DALIQLDMSE FAEKHTVSRL FGAPPGYVGY
DEGGQLTEKV RRRPFSVVLF DEVEKAHPDI FNSLLQILED GHLSDAQGRV VDFKNTVIIM
TTNLGSKDIG KSVATGFQST ESGAMDYEEM KSHVNRELKQ QFRPEFLNRV DDLIVFPQLT
KEEVRQIVDL MVARLDKRLA EQQMTIELTD AAKDLLAERG FDPVLGARPL RRAIQRDIED
ALSEKILFGE IERGQKVIVD AEGESILGEF IFRGEPWEQG EAEVAALREA EEAAAGGGGG
ASSPLRIPST PIGRDGGASP AAEPGH
//
