ID F3PUM3_9BACE Unreviewed; 515 AA.
AC F3PUM3;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Oxidoreductase, NAD-binding domain protein {ECO:0000313|EMBL:EGF56094.1};
GN ORFNames=HMPREF9446_02496 {ECO:0000313|EMBL:EGF56094.1};
OS Bacteroides fluxus YIT 12057.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=763034 {ECO:0000313|EMBL:EGF56094.1, ECO:0000313|Proteomes:UP000003416};
RN [1] {ECO:0000313|EMBL:EGF56094.1, ECO:0000313|Proteomes:UP000003416}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIT 12057 {ECO:0000313|EMBL:EGF56094.1,
RC ECO:0000313|Proteomes:UP000003416};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
CC -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109
CC subfamily. {ECO:0000256|ARBA:ARBA00009329}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGF56094.1}.
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DR EMBL; AFBN01000047; EGF56094.1; -; Genomic_DNA.
DR RefSeq; WP_009125751.1; NZ_GL882644.1.
DR AlphaFoldDB; F3PUM3; -.
DR STRING; 763034.HMPREF9446_02496; -.
DR eggNOG; COG0673; Bacteria.
DR HOGENOM; CLU_046965_0_0_10; -.
DR Proteomes; UP000003416; Unassembled WGS sequence.
DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR049303; Glyco_hydro_109_C.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43818; BCDNA.GH03377; 1.
DR PANTHER; PTHR43818:SF1; GLYCOSYL HYDROLASE FAMILY 109 PROTEIN; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF21252; Glyco_hydro_109_C; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000003416};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..515
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003305871"
FT DOMAIN 67..191
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 203..354
FT /note="Glycosyl hydrolase 109 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21252"
SQ SEQUENCE 515 AA; 57345 MW; D16B023AD7F37259 CRC64;
MKKIGLLVLS LCFAFGACST QTATTVQTTE KGTQWEWKNG TIVVQTPERP AGQKSVLGLT
VPKMEVVRVG FVGLGMRGPG AVARFTYIPG TQIVALCDYE QERAERCQKY LEKASLPKAA
VYSGATGYEE LCKRDDIDLV YIAADWLHHF PVAKCALENG KHVAIEVPSA MNLQECWDLI
NLSEANRKHC MILENCCYDW FEMNTLNMAQ QGVFGEVIRA QGAYIHNLEP FWDYYWKNGE
GDKLGWRLDY NMKHRGDVYA THGLGPVAQA LDIHRGDRVT TLVAMDTKSV VGKALVEDRT
DSTCNNFRNG DHTTTLLRTA NGKVIEIQHN VMTPQPYNRL YQLTGTKGFA NKYPVEGYAL
DAKQLSASGV QPKVDDLSSH GFLPDAEMKA LVEKYQHPIL KKYGEMAKEV GGHGGMDFIM
DSRLVYCLQN GLPLDMDVYD LAEWCCLAEL GELSMDNGCA AVEFPDFTRG EWNVVKGYKH
AYAAPEEEAA TAKKAAEFTA KLKEQGAKEW AAEKK
//
