ID F3QUA3_9BACT Unreviewed; 625 AA.
AC F3QUA3;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE RecName: Full=Tetracycline resistance protein TetQ {ECO:0000256|ARBA:ARBA00013902};
DE Flags: Fragment;
GN ORFNames=HMPREF9442_01772 {ECO:0000313|EMBL:EGG54005.1};
OS Paraprevotella xylaniphila YIT 11841.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Paraprevotella.
OX NCBI_TaxID=762982 {ECO:0000313|EMBL:EGG54005.1, ECO:0000313|Proteomes:UP000005546};
RN [1] {ECO:0000313|EMBL:EGG54005.1, ECO:0000313|Proteomes:UP000005546}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIT 11841 {ECO:0000313|EMBL:EGG54005.1,
RC ECO:0000313|Proteomes:UP000005546};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Abolishes the inhibitory effect of tetracyclin on protein
CC synthesis by a non-covalent modification of the ribosomes.
CC {ECO:0000256|ARBA:ARBA00003987}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG54005.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFBR01000047; EGG54005.1; -; Genomic_DNA.
DR RefSeq; WP_008627130.1; NZ_GL883847.1.
DR AlphaFoldDB; F3QUA3; -.
DR STRING; 762982.HMPREF9442_01772; -.
DR eggNOG; COG0480; Bacteria.
DR HOGENOM; CLU_002794_4_2_10; -.
DR OrthoDB; 9801472at2; -.
DR Proteomes; UP000005546; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR CDD; cd03711; Tet_C; 1.
DR CDD; cd03690; Tet_II; 1.
DR CDD; cd16258; Tet_III; 1.
DR CDD; cd01684; Tet_like_IV; 1.
DR CDD; cd04168; TetM_like; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR035650; Tet_C.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43261:SF1; RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43261; TRANSLATION ELONGATION FACTOR G-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR PRINTS; PR01037; TCRTETOQM.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Elongation factor {ECO:0000313|EMBL:EGG54005.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 1..228
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EGG54005.1"
SQ SEQUENCE 625 AA; 70561 MW; 6C9D17C5E11C36D7 CRC64;
TSVTENLLFA SGATEKCGRV DNGDTITDSM DIEKRRGITV RASTTSIIWN GVKCNIIDTP
GHMDFIAEVE RTFKMLDGAV LILSAKEGIQ AQTKLLFNTL QKLQIPTIIF INKIDRAGVN
LERLYMDIKT NLSQDVLFMQ TVVDGSVYPV CSQTYIKEEY KEFVCNHDDD ILERYLADSE
ISPADYWNTI IALVAKAKVY PVLHGSAMFN IGINELLDAI SSFILPPASV SNRLSAYLYK
IEHDPKGHKR SFLKIIDGSL RLRDVVRIND SEKFIKIKNL KTIYQGREIN VDEVGANDIA
IVEDMEDFRI GDYLGAEPCL IQGLSHQNPA LKSSVRPDKP EERSKVISAL NTLWIEDPSL
SFSINSYSDE LEISLYGLTQ KEIIQTLLEE RFSVKVHFDE VKTIYKERPV KKVNKIIQIE
VPPNPYWATI GLTLEPLPLG AGLQIESDIS YGYLNHSFQN AVFEGIRMSC QSGLHGWEVT
DLKVTFTQAE YYSPVSTPAD FRQLTPYVFR LALQQSGVDI LEPMLCFELQ IPQVASSKAI
TDLQKMMSEI EDISCNNEWC HIKGKVPLNT SKDYASEVSS YTKGLGIFMV KPCGYQITKD
GYSDNIRMNE KDKLLFMFQK SMSLK
//
