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Database: UniProt
Entry: F3ZNN2_9BACE
LinkDB: F3ZNN2_9BACE
Original site: F3ZNN2_9BACE 
ID   F3ZNN2_9BACE            Unreviewed;       470 AA.
AC   F3ZNN2;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   25-OCT-2017, entry version 42.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=Bcop_0001 {ECO:0000313|EMBL:EGJ70221.1};
OS   Bacteroides coprosuis DSM 18011.
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=679937 {ECO:0000313|EMBL:EGJ70221.1, ECO:0000313|Proteomes:UP000018439};
RN   [1] {ECO:0000313|EMBL:EGJ70221.1, ECO:0000313|Proteomes:UP000018439}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DSM 18011 {ECO:0000313|EMBL:EGJ70221.1};
RX   PubMed=21677860; DOI=10.4056/sigs.1784330;
RA   Land M., Held B., Gronow S., Abt B., Lucas S., Del Rio T.G., Nolan M.,
RA   Tice H., Cheng J.F., Pitluck S., Liolios K., Pagani I., Ivanova N.,
RA   Mavromatis K., Mikhailova N., Pati A., Tapia R., Han C., Goodwin L.,
RA   Chen A., Palaniappan K., Hauser L., Brambilla E.M., Rohde M.,
RA   Goker M., Detter J.C., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P., Lapidus A.;
RT   "Non-contiguous finished genome sequence of Bacteroides coprosuis type
RT   strain (PC139).";
RL   Stand. Genomic Sci. 4:233-243(2011).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CM001167; EGJ70221.1; -; Genomic_DNA.
DR   RefSeq; WP_006743379.1; NZ_CM001167.1.
DR   STRING; 679937.Bcop_0001; -.
DR   EnsemblBacteria; EGJ70221; EGJ70221; Bcop_0001.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000018439; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018439};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018439}.
FT   DOMAIN      166    296       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      377    446       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     174    181       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   470 AA;  53963 MW;  D592F3D429E56214 CRC64;
     MNKPVHVALW NDCLNIIRDN VAESTYNTWF APIIPLKFED KTLVIQVPSQ FFYEFLEEKF
     VDLLRHTLYQ VIGEGAKLMY NVMVDRSASA TVNLEASNRS TAVRKNNISP AAPRTRIPQA
     PQAPAIQELD PRLNPDYTFE TFIEGNSNKL SRSVAEAVAE NPAKTVFNPL FIHGNSGVGK
     THLANAIGLR IKERYPEKRV LYVSAHLFQI QYTDSVRNNT TNDFINFYQT IDVLIIDDIQ
     EFAGVVKTQN TFFHIFNHLH QNGKQLILTS DLPPVLLQGM EDRLLTRFKW GMVAELERPS
     VELRKDILRN KIHRDGLDFP TEVITYIAEN VDDSVRDLEG IVISIMAHST IYNKEIDLDL
     AQRIVKKVVR SEKKVITIDN ILTAVTDYFK IEPKQIHSRS RKREVVQARH FAMFLAKKYT
     EYSTPKIGKF IGNRNHSTVL HACKTVKHQC EVDKSYRADM EAVQELLHKK
//
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