ID F3ZPR7_9BACE Unreviewed; 698 AA.
AC F3ZPR7;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Sulfatase {ECO:0000313|EMBL:EGJ71654.1};
GN ORFNames=Bcop_1459 {ECO:0000313|EMBL:EGJ71654.1};
OS Bacteroides coprosuis DSM 18011.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=679937 {ECO:0000313|EMBL:EGJ71654.1, ECO:0000313|Proteomes:UP000018439};
RN [1] {ECO:0000313|EMBL:EGJ71654.1, ECO:0000313|Proteomes:UP000018439}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18011 {ECO:0000313|EMBL:EGJ71654.1,
RC ECO:0000313|Proteomes:UP000018439};
RX PubMed=21677860; DOI=10.4056/sigs.1784330;
RA Land M., Held B., Gronow S., Abt B., Lucas S., Del Rio T.G., Nolan M.,
RA Tice H., Cheng J.F., Pitluck S., Liolios K., Pagani I., Ivanova N.,
RA Mavromatis K., Mikhailova N., Pati A., Tapia R., Han C., Goodwin L.,
RA Chen A., Palaniappan K., Hauser L., Brambilla E.M., Rohde M., Goker M.,
RA Detter J.C., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P., Lapidus A.;
RT "Non-contiguous finished genome sequence of Bacteroides coprosuis type
RT strain (PC139).";
RL Stand. Genomic Sci. 4:233-243(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CM001167; EGJ71654.1; -; Genomic_DNA.
DR AlphaFoldDB; F3ZPR7; -.
DR eggNOG; COG1368; Bacteria.
DR HOGENOM; CLU_014653_1_0_10; -.
DR Proteomes; UP000018439; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16015; LTA_synthase; 1.
DR Gene3D; 3.30.1120.80; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012160; LtaS-like.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF005091; Mmb_sulf_HI1246; 2.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Manganese {ECO:0000256|PIRSR:PIRSR005091-2};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR005091-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000018439};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 339..609
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT ACT_SITE 387
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-1"
FT BINDING 347
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 387
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 505
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-2"
FT BINDING 558
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 559
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
SQ SEQUENCE 698 AA; 79929 MW; 2760FEE8179F897D CRC64;
MAKESFSLKK LMPSSKAGMF LKGLGNILLL FIVIGLIVRI LFLFNSQTAT SFTMLEQLEI
FGLGMINDVA MAIILNVFLW LSLIGVGERK YKFPFGYFIL GFFILSWIYL TFTNTVFHEY
NKSLARILKY LALYKSISFG LRLFIPSIRQ KWSYISYVVL IFVYVLAMLT NAVSEYFFWD
EFGLRYNFIA VDYLVYTHEV IGNILESYSI IPLLLVLITV AAVITFFMVR KDSVFFRETV
SFKTKASVSI AYLVLVGGSM WLVNATKYFQ NNQDVFLNEL QANGIFKFYE AFKSSALDYD
TFYLTLGIHD VKSFIKGRYN CEEGADSYPI TYMQPEVHKN IVLITVESLS ADFLAHFGNT
DHLTPRLDSL IQHSLVFNNL YATGNRTVRG LEALTLSLPP SPGESIIKRP DNSNLFSVGK
VLKEKGYTVQ YIYGGDSYFD NMGTFFSGNG YEIIDSKDID KKKITYQNVW GVCDEDLYTK
ALEVFDDNEK LNKPFFSHLM TVSNHRPFTY PSGKVSISPE TKTRSGAVEY TDYAIGDFIE
RAKSLSWFEN TIFIVVADHC ASSAGKVELP LDKYHIPALI YAPGFVEPQE VNTRVSQIDI
MPTVLGMLNL NYESQFYGMD IFHNVNYNPR AFIATYQDLG YWSGDILTVL SPVKRNRQFQ
IIQNGFMFEE IPLKTEHEES LDDAISYYQS LELKEWEE
//
