ID F4A0T3_MAHA5 Unreviewed; 694 AA.
AC F4A0T3;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=NHL repeat containing protein {ECO:0000313|EMBL:AEE96979.1};
GN OrderedLocusNames=Mahau_1798 {ECO:0000313|EMBL:AEE96979.1};
OS Mahella australiensis (strain DSM 15567 / CIP 107919 / 50-1 BON).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacterales Family IV. Incertae Sedis; Mahella.
OX NCBI_TaxID=697281 {ECO:0000313|EMBL:AEE96979.1, ECO:0000313|Proteomes:UP000008457};
RN [1] {ECO:0000313|Proteomes:UP000008457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15567 / CIP 107919 / 50-1 BON
RC {ECO:0000313|Proteomes:UP000008457};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Teshima H., Brettin T.,
RA Detter J.C., Han C., Tapia R., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S., Pukall R.,
RA Steenblock K., Schneider S., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Mahella australiensis DSM 15567.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEE96979.1, ECO:0000313|Proteomes:UP000008457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15567 / CIP 107919 / 50-1 BON
RC {ECO:0000313|Proteomes:UP000008457};
RX PubMed=21886860;
RA Sikorski J., Teshima H., Nolan M., Lucas S., Hammon N., Deshpande S.,
RA Cheng J.F., Pitluck S., Liolios K., Pagani I., Ivanova N., Huntemann M.,
RA Mavromatis K., Ovchinikova G., Pati A., Tapia R., Han C., Goodwin L.,
RA Chen A., Palaniappan K., Land M., Hauser L., Ngatchou-Djao O.D., Rohde M.,
RA Pukall R., Spring S., Abt B., Goker M., Detter J.C., Woyke T., Bristow J.,
RA Markowitz V., Hugenholtz P., Eisen J.A., Kyrpides N.C., Klenk H.P.,
RA Lapidus A.;
RT "Complete genome sequence of Mahella australiensis type strain (50-1
RT BON).";
RL Stand. Genomic Sci. 4:331-341(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002360; AEE96979.1; -; Genomic_DNA.
DR RefSeq; WP_013781407.1; NC_015520.1.
DR AlphaFoldDB; F4A0T3; -.
DR STRING; 697281.Mahau_1798; -.
DR KEGG; mas:Mahau_1798; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG3391; Bacteria.
DR HOGENOM; CLU_024978_0_0_9; -.
DR OrthoDB; 9799230at2; -.
DR Proteomes; UP000008457; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd05819; NHL; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 2.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR001258; NHL_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR006977; Yip1_dom.
DR PANTHER; PTHR24104; E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED; 1.
DR PANTHER; PTHR24104:SF25; GLYCOPROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF01436; NHL; 1.
DR Pfam; PF13414; TPR_11; 1.
DR Pfam; PF04893; Yip1; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51125; NHL; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008457};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..694
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003304129"
FT TRANSMEM 448..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 520..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 553..574
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 586..607
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 619..638
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 650..672
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 60..95
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT DOMAIN 498..667
FT /note="Yip1"
FT /evidence="ECO:0000259|Pfam:PF04893"
SQ SEQUENCE 694 AA; 78155 MW; 3D5D6B6E72A069EA CRC64;
MSKINGYILA ISIVLLILLN GSVSAYAAPP YPTYTYDNAL EAAPSPAGYL PHDVLIGADF
GIEAFNAPQD ICIAPDGEIY IADTGNNRII VLNSQLKLQK IIKGFINLGK QDNFKLPEGV
YVNDEEIYVA DTQNGRIIIL DKKGNLIKII GKPVSDIIPS DFAYKPQKVV ADKAGRIYVV
ASGVVEGILQ FTPDGQFNRF FGSNRVKANP VELLWRRILT REQVAQRELF VPIEYSNLYI
DHDGFLYTST RNATEDQIKR LNAAGDNIIR HSERLGNRYG DILPTNEPFQ FLDISVDTDG
NIFALENSSG RIYIYSALGD MLFVIGGRGE QKGLFANPVA LEQKNGKIFV VDGSKNSLTI
LKITDFGNDV LKANSYYMQG RYEDALQPWQ KVLKRNANYD LAYVGLGNAY LKEEKYAQAM
DVFKLARYRK GYSEALKEYR TQVLRENFSF IMTLLCFIIA GLYVLNKVLH RHGVYLSKSI
REYMGKDGTM NTVLYALYVI IHPFDGFWDL KHYKKKAGTA SVIILTLAVI IFMLRMALTS
FLFNSTVPEE MNILTQITVI LLPLTAWVVI NWSISTLMDG EATMKHIWIS SCYALTPLIL
LYSFQIILSN FITIEEGTFY YFIDAVAIIW TLALTIIGNM TVQDYTMGKT VTVSCFSVFG
ILAVIFLGMV FFSALQQLIK FITTLYLEIK YMVL
//
