ID   F4C6J4_SPHS2            Unreviewed;       396 AA.
AC   F4C6J4;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=3-dehydroquinate synthase {ECO:0000313|EMBL:ADZ77030.1};
DE            EC=4.2.3.4 {ECO:0000313|EMBL:ADZ77030.1};
GN   OrderedLocusNames=Sph21_0448 {ECO:0000313|EMBL:ADZ77030.1};
OS   Sphingobacterium sp. (strain 21).
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Sphingobacterium.
OX   NCBI_TaxID=743722 {ECO:0000313|EMBL:ADZ77030.1};
RN   [1] {ECO:0000313|EMBL:ADZ77030.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=21 {ECO:0000313|EMBL:ADZ77030.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Siebers A.K.,
RA   Allgaier M., Thelen M.P., Hugenholtz P., Woyke T.;
RT   "Complete sequence of Sphingobacterium sp. 21.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC         Evidence={ECO:0000256|ARBA:ARBA00001911};
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DR   EMBL; CP002584; ADZ77030.1; -; Genomic_DNA.
DR   AlphaFoldDB; F4C6J4; -.
DR   STRING; 743722.Sph21_0448; -.
DR   KEGG; shg:Sph21_0448; -.
DR   PATRIC; fig|743722.3.peg.487; -.
DR   eggNOG; COG0337; Bacteria.
DR   HOGENOM; CLU_001201_0_4_10; -.
DR   OrthoDB; 9806583at2; -.
DR   GO; GO:0003856; F:3-dehydroquinate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd08198; DHQS-like; 1.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR   InterPro; IPR030960; DHQS/DOIS.
DR   PANTHER; PTHR43622; 3-DEHYDROQUINATE SYNTHASE; 1.
DR   PANTHER; PTHR43622:SF7; 3-DEHYDROQUINATE SYNTHASE, CHLOROPLASTIC; 1.
DR   Pfam; PF01761; DHQ_synthase; 1.
DR   SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:ADZ77030.1};
KW   NAD {ECO:0000256|ARBA:ARBA00023027}.
FT   DOMAIN          83..333
FT                   /note="3-dehydroquinate synthase"
FT                   /evidence="ECO:0000259|Pfam:PF01761"
SQ   SEQUENCE   396 AA;  44855 MW;  BB20EEB2DAE7CF89 CRC64;
     MKHILKQHLT VTFQYEVYFS ENIFSIDNSL FRDALAPYLK PGLVRQLLFV IDEELSLAHP
     GLLKQIDVYF QGQVHLALVK EKIIIPGGEV AKNSPYYFNQ IVEAIHRHKV DRHSFVVAIG
     GGSVLDVAGY AAAVSHRGIK HIRVPTTVLS QDDSGVGIKN GINFFGKKNF LGTFAPPIAV
     FNDYQLLETL SDRHWVAGIA EAIKVALIKD ATFFEWLRDQ VDGILKRNAD TMKYLIWRSA
     QLHMDHIASG DPFELGSSRP LDFGHWSAHK IEQLSDFQIL HGEAVAIGIA LDTTYSFLQG
     YLNECDYKEI LRVLQAYELP IFHQLLKDER VISDLLDGLE EFREHLGGKL TIMLLRAVGV
     GLEVHEMDHD RIREALARLK KLDEVQQQRK LVSLPD
//