ID F4CUN3_PSEUX Unreviewed; 957 AA.
AC F4CUN3;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=NADPH dehydrogenase {ECO:0000313|EMBL:AEA26347.1};
DE EC=1.6.99.1 {ECO:0000313|EMBL:AEA26347.1};
GN OrderedLocusNames=Psed_4184 {ECO:0000313|EMBL:AEA26347.1};
OS Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 /
OS CB1190).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=675635 {ECO:0000313|EMBL:AEA26347.1, ECO:0000313|Proteomes:UP000007809};
RN [1] {ECO:0000313|EMBL:AEA26347.1, ECO:0000313|Proteomes:UP000007809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 55486 / DSM 44775 / JCM 13855 / CB1190
RC {ECO:0000313|Proteomes:UP000007809};
RX PubMed=21725009; DOI=10.1128/JB.00415-11;
RA Sales C.M., Mahendra S., Grostern A., Parales R.E., Goodwin L.A., Woyke T.,
RA Nolan M., Lapidus A., Chertkov O., Ovchinnikova G., Sczyrba A.,
RA Alvarez-Cohen L.;
RT "Genome sequence of the 1,4-dioxane-degrading Pseudonocardia dioxanivorans
RT strain CB1190.";
RL J. Bacteriol. 193:4549-4550(2011).
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
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DR EMBL; CP002593; AEA26347.1; -; Genomic_DNA.
DR AlphaFoldDB; F4CUN3; -.
DR STRING; 675635.Psed_4184; -.
DR KEGG; pdx:Psed_4184; -.
DR eggNOG; COG0446; Bacteria.
DR eggNOG; COG1902; Bacteria.
DR eggNOG; COG4126; Bacteria.
DR HOGENOM; CLU_308325_0_0_11; -.
DR OrthoDB; 3169239at2; -.
DR Proteomes; UP000007809; Chromosome.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0003959; F:NADPH dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0018548; F:pentaerythritol trinitrate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0036361; F:racemase activity, acting on amino acids and derivatives; IEA:InterPro.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.12500; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR015942; Asp/Glu/hydantoin_racemase.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR001155; OxRdtase_FMN_N.
DR PANTHER; PTHR42917; 2,4-DIENOYL-COA REDUCTASE; 1.
DR PANTHER; PTHR42917:SF2; 2,4-DIENOYL-COA REDUCTASE [(2E)-ENOYL-COA-PRODUCING]; 1.
DR Pfam; PF01177; Asp_Glu_race; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF00724; Oxidored_FMN; 1.
DR SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:AEA26347.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007809}.
FT DOMAIN 13..341
FT /note="NADH:flavin oxidoreductase/NADH oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00724"
FT DOMAIN 400..439
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 957 AA; 102992 MW; A0FCCF38BBF83CF3 CRC64;
MTDRNDAPPP ERVFRPLTLG PVTLRNRIFV SAHTTNLGER HEVSDRLVAY HRERAAGGVG
LVVTEGLRVH PTSLKRPEAL SVWSDDAVAP LRRLTAAVQG EGAAIFAQIL HSGREAADDY
TRTPSWGPSP IPWSRGAAVP HAMTTDEIDE LVDCFAGGVL RAAAAGFDGV EIHLGHGHLL
QQFLSPISNG RDDEYGGTPA NRARLVERVL TRTRGLVPAH MAFGVRISAE EFVDGGLGVD
VMSQYAAQWA SRYRLDFVDV SHSAYVGGPS LSTQMADMSH GPAPFAHLGK AVRDRLPDDV
ATLLACRIDS LDVAEDVLAA GCADATAMTR AHIADPGLNR KHRGGEVVRR CTSCNQLCIG
RSSGGLPISC VVNPEVGLEE AWREAYAAAD RVVTGGRPRL LVVGGGPAGM EAALTATRWA
DVTLVEREPA LGGALRTARA LHGRSGWARL VEDQERTCRE CGVELRQGVA FDAGLLTAEP
WDGIVLATGA VVGPRWSDDR DPVRCFGSGV PDPAGVRRAA VHDDRGGWEA WGVVAHLVHH
GVETHYVTPL QSLAPGVTIY SRLGLLAGLR ASDLLHVHLM TTVSGWRDRV LTLRASLPDT
ETAVADVDAL WDAGVATPAA PRRLPVPHRV VGDAYAPRGA GWAVYSGRLG ALRILADIRH
RDDPVARSTA QRGLDADRRV AHVVPGRTVK IWFQKHTIIG RNPWLDETYP RHATAMLGDR
ADVTFVGLPG AVYDDQIPAD YVRFGQIEVF FSWYFASQAV KAERAGYDAY VIGTSQDPGL
AMARSLVSIP VLAYGETAFT LARTHGLRFG VVGFIPELEE ALTANIRALG LADSCVGFRY
LEGGRDLVTS ATRDGRTDAL AAAMDEAATT LRRTGAQCIV PGEGLPNEML WAAGIHEVGG
LPVIDCDGLV MLTAEMHARA RRLRVWAPDD DSYDTRRAPD EVIDRMTEIF SPGGGRW
//
