ID F4ITY4_ARATH Unreviewed; 331 AA.
AC F4ITY4;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Ubiquitin-conjugating enzyme/RWD-like protein {ECO:0000313|EMBL:AEC09592.1};
GN OrderedLocusNames=At2g38830 {ECO:0000313|EMBL:AEC09592.1};
GN ORFNames=F13I13.6 {ECO:0000313|EMBL:AEC09592.1}, F13I13_6
GN {ECO:0000313|EMBL:AEC09592.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AEC09592.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:AEC09592.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S., Shea T.P., Benito M.I., Town C.D.,
RA Fujii C.Y., Mason T., Bowman C.L., Barnstead M., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SUBCELLULAR LOCATION: Endosome {ECO:0000256|ARBA:ARBA00004177}.
CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UEV
CC subfamily. {ECO:0000256|ARBA:ARBA00009594}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002685; AEC09592.1; -; Genomic_DNA.
DR RefSeq; NP_181417.2; NM_129440.3.
DR AlphaFoldDB; F4ITY4; -.
DR SMR; F4ITY4; -.
DR STRING; 3702.F4ITY4; -.
DR PaxDb; 3702-AT2G38830-1; -.
DR ProteomicsDB; 198207; -.
DR EnsemblPlants; AT2G38830.1; AT2G38830.1; AT2G38830.
DR GeneID; 818467; -.
DR Gramene; AT2G38830.1; AT2G38830.1; AT2G38830.
DR KEGG; ath:AT2G38830; -.
DR TAIR; AT2G38830; -.
DR eggNOG; KOG2391; Eukaryota.
DR HOGENOM; CLU_017548_0_0_1; -.
DR InParanoid; F4ITY4; -.
DR OMA; PDQKWLI; -.
DR OrthoDB; 37962at2759; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; F4ITY4; baseline and differential.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR Gene3D; 6.10.140.820; -; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR037202; ESCRT_assembly_dom.
DR InterPro; IPR017916; SB_dom.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR008883; UEV_N.
DR PANTHER; PTHR23306; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED; 1.
DR PANTHER; PTHR23306:SF21; UBIQUITIN-CONJUGATING ENZYME_RWD-LIKE PROTEIN; 1.
DR Pfam; PF05743; UEV; 1.
DR Pfam; PF09454; Vps23_core; 1.
DR SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS51312; SB; 1.
DR PROSITE; PS51322; UEV; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 18..163
FT /note="UEV"
FT /evidence="ECO:0000259|PROSITE:PS51322"
FT DOMAIN 267..331
FT /note="SB"
FT /evidence="ECO:0000259|PROSITE:PS51312"
SQ SEQUENCE 331 AA; 38131 MW; CB18AED30EDF0758 CRC64;
MAASSSSSSQ VKFIEKALLA TGSFALSYTD PDQKWLIRKH LTSLLQDYPN FELSTDTFNH
NNGAKVQLFC LEGSLRIRSS TTQLPTVQLT IWIHENYPLT PPLVFINPNS IPIRNNHPFI
NSSGYTKSRY IETWEHPRCN LLDFIRNLKK VLANDHPFLH TDSLIPTRNQ SVSRTEALDR
LATSLHYDVL TIMERSEEEI ENLWKLQSEV KQRSESVKSI ITELEIERGT LKVRALKLKE
DSDVLTTWVE MNYLKLTSMD MGRIEEMFEI ESEVEGLAGD DAIEDVLRVL EEAAERGELE
IGSYLKQVRV LAREQFFLKH LSSFKTQNFH I
//
