ID F4KJE3_PORAD Unreviewed; 493 AA.
AC F4KJE3;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Succinate CoA transferase {ECO:0000313|EMBL:AEE12586.1};
DE EC=3.1.2.1 {ECO:0000313|EMBL:AEE12586.1};
GN OrderedLocusNames=Poras_0636 {ECO:0000313|EMBL:AEE12586.1};
OS Porphyromonas asaccharolytica (strain ATCC 25260 / DSM 20707 / BCRC 10618 /
OS JCM 6326 / LMG 13178 / VPI 4198) (Bacteroides asaccharolyticus).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC Porphyromonas.
OX NCBI_TaxID=879243 {ECO:0000313|EMBL:AEE12586.1, ECO:0000313|Proteomes:UP000006545};
RN [1] {ECO:0000313|Proteomes:UP000006545}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25260 / DSM 20707 / VPI 4198
RC {ECO:0000313|Proteomes:UP000006545};
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Pagani I., Lu M.,
RA Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S.,
RA Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Porphyromonas asaccharolytica DSM 20707.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; CP002689; AEE12586.1; -; Genomic_DNA.
DR RefSeq; WP_013760153.1; NC_015501.1.
DR AlphaFoldDB; F4KJE3; -.
DR STRING; 879243.Poras_0636; -.
DR KEGG; pah:Poras_0636; -.
DR eggNOG; COG0427; Bacteria.
DR HOGENOM; CLU_019748_3_0_10; -.
DR OrthoDB; 9801795at2; -.
DR Proteomes; UP000006545; Chromosome.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0003986; F:acetyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:AEE12586.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006545};
KW Transferase {ECO:0000313|EMBL:AEE12586.1}.
FT DOMAIN 7..210
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 317..459
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 284
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 374
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 378
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 398
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 493 AA; 53841 MW; 680D71C44B5A46C5 CRC64;
MSYPIMTAEE AARLVHDGDQ VGFSGFTPAG CPKVVPQAIA HYAEEEHAAG RPFRIGVFTG
ASTGDRLDGA LARAHAIKFR APYQSNKDLR AEINSGEVAY CDMHLSQLAQ EMRAGFFGKI
HVAIVEAAEL TEDGQLVPTT GVGILPTICR LADRIIVEIN DRHPAKIRGL HDIAEPLDPP
ARRELPIYKP SDRVGKPYVQ LDPKKVVAVV KTSEPNDDGG FAPLDEVTQA IGDNVTKFLE
EEIRTGRIPR EFLPLQSGVG NIANAVLASV GKSPKIPPFE VYTEVIQDAV IGLMKEGRVK
FASGCSLSVS RNVILDIYQN WDFFKDKLLL RPEEYSNNPG IVRRLGVITM NTALEADIYG
NINSTHVLGT KMMNGIGGSG DFTRNGYISI FTTPSTAKGG AISAIVPMVS HVDHSEHSVK
VLITEYGIAD LRGLSPRQRA ERIIENCAHP DYRPLLRAYL AQASEGQTPV CLEKAFAFHK
AFAETKDMRQ AKF
//
