ID   F4LK91_TREBD            Unreviewed;      1112 AA.
AC   F4LK91;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=Transcriptional regulator, AraC family {ECO:0000313|EMBL:AEE15480.1};
GN   OrderedLocusNames=Trebr_0020 {ECO:0000313|EMBL:AEE15480.1};
OS   Treponema brennaborense (strain DSM 12168 / CIP 105900 / DD5/3).
OC   Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC   Treponema.
OX   NCBI_TaxID=906968 {ECO:0000313|EMBL:AEE15480.1, ECO:0000313|Proteomes:UP000006546};
RN   [1] {ECO:0000313|Proteomes:UP000006546}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12168 / CIP 105900 / DD5/3
RC   {ECO:0000313|Proteomes:UP000006546};
RA   Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Pagani I.,
RA   Teshima H., Detter J.C., Tapia R., Han C., Land M., Hauser L.,
RA   Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Gronow S.,
RA   Wellnitz S., Brambilla E., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Treponema brennaborense DSM 12168.";
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002696; AEE15480.1; -; Genomic_DNA.
DR   RefSeq; WP_013757200.1; NC_015500.1.
DR   AlphaFoldDB; F4LK91; -.
DR   STRING; 906968.Trebr_0020; -.
DR   KEGG; tbe:Trebr_0020; -.
DR   eggNOG; COG1609; Bacteria.
DR   eggNOG; COG2205; Bacteria.
DR   eggNOG; COG2207; Bacteria.
DR   HOGENOM; CLU_283836_0_0_12; -.
DR   OrthoDB; 9799345at2; -.
DR   Proteomes; UP000006546; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR018062; HTH_AraC-typ_CS.
DR   InterPro; IPR046335; LacI/GalR-like_sensor.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR   PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR   PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR   Pfam; PF12833; HTH_18; 1.
DR   Pfam; PF13377; Peripla_BP_3; 1.
DR   PRINTS; PR00032; HTHARAC.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006546};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          1013..1111
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000259|PROSITE:PS01124"
SQ   SEQUENCE   1112 AA;  123814 MW;  77FABE75D4F28DC9 CRC64;
     MKNTAKRIGL TLATVHTGSS LKLWTELAGE AESSGNPFFV FSGGRLNSRR DSEYLRNGVY
     ALANKENLDG LISWSSSIGG FVSIEEIIQF HHRLEPLPFV TIGQKIDGHA FANFDAYTGM
     KNLTLHFIRE HGAERLAFIR GPENHMSAAE RFTGFCDAVT ESGLTLDDTL ITSPFPWGMG
     ESAAAQLFAE RRLIPGKDFD TLIGSSDMLV FAAVRYFERQ GFSVPQHFRT GGFNDSAESL
     IASCPFSTVH MPYTDLARTA YRMITSVLEN PAAPISDEKI EAPVIIRESC GCNRSEPFIF
     RADAPDMQGH EADMQEPAPE ARCYAPKGPE HASYSVQTLA SRICALITSS HPILPGLIEK
     AVAAFSQKAR VQCEALLDQI LFYYLKSDGD LSVLPAIGDL IRRAKLVPES YFMEMHEYML
     FSIPKIQNRI FSAKKYESMQ LIDILNRLKC ELLRAHSRKE LLSILKELLP QIGVHTMSIV
     LYEDDDLSSY MGGFAPDGRP ESWTGSGYCR TVSQLHESPD VFPSQLLFPP DIGRYYKEGC
     FMVQPLFIEN QPIGYLLTNI AFYDGGVYED LRAAISSALQ GIFLFEQTAK ARQIAESAEF
     AKTEFFANVG SGLCDPLNEI EDKLDQIGLT LAAHPEATDI IGEQLLFIKA QVAAQLREMS
     VLVDLTRSQV NDLPMDKTLV YVPDILPEDV KPATDVPYPL IFGDREQIEK ALRVIAEKSA
     APVQICAEAS GLSLRFTYAD DSVFGDWSYP VYLLAEKIIA LHFGRVIKSG AACTVVFPYP
     NLAGLPPLKM HESPECVCTV SDFTAAPRVL PDLSAYPFDS EVVPGAEEVR PFLLALLPDA
     TPMQNWVRLY SLRNDANVFR APVACYGKEF AGKSFMEVLE SKIRTEKIEP ILFIGTAKTR
     YPLWATDVNS ISIGSINELD RILAEITPAL IVFENAEEAD IKRIRQISKT VLTPIAVLPD
     SIESEETVKM LCAYPKIILC NQGAAESEQF AKRVHDILAG IEILPPHTGA LVKNAILYLN
     RHAASQIVRW KLADAVCVSE DYLTRIFHKE IGLSLWEYLN RYRIHLATKM LLETNATIYE
     IAEKTGFQDQ AYFCRVFKKI YGIPPGKIRT KQ
//