ID F4LWD1_TEPAE Unreviewed; 419 AA.
AC F4LWD1;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Glucokinase {ECO:0000313|EMBL:CDI40789.1};
DE EC=2.7.1.2 {ECO:0000313|EMBL:CDI40789.1};
GN OrderedLocusNames=TEPIRE1_1711 {ECO:0000313|EMBL:CDI40789.1};
OS Tepidanaerobacter acetatoxydans (strain DSM 21804 / JCM 16047 / Re1).
OC Bacteria; Bacillota; Clostridia; Thermosediminibacterales;
OC Tepidanaerobacteraceae; Tepidanaerobacter.
OX NCBI_TaxID=1209989 {ECO:0000313|EMBL:CDI40789.1, ECO:0000313|Proteomes:UP000010802};
RN [1] {ECO:0000313|Proteomes:UP000010802}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Re1 {ECO:0000313|Proteomes:UP000010802};
RX PubMed=23469343; DOI=10.1128/genomeA.00213-12;
RA Manzoor S., Bongcam-Rudloff E., Schnurer A., Muller B.;
RT "First genome sequence of a syntrophic acetate-oxidizing bacterium,
RT Tepidanaerobacter acetatoxydans strain Re1.";
RL Genome Announc. 1:E00213-E00213(2013).
CC -!- FUNCTION: Transcriptional repressor of xylose-utilizing enzymes.
CC {ECO:0000256|ARBA:ARBA00002486}.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
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DR EMBL; HF563609; CDI40789.1; -; Genomic_DNA.
DR AlphaFoldDB; F4LWD1; -.
DR STRING; 1209989.TepRe1_1589; -.
DR KEGG; tae:TepiRe1_1711; -.
DR KEGG; tep:TepRe1_1589; -.
DR eggNOG; COG1846; Bacteria.
DR eggNOG; COG1940; Bacteria.
DR HOGENOM; CLU_036604_13_5_9; -.
DR Proteomes; UP000010802; Chromosome.
DR GO; GO:0004340; F:glucokinase activity; IEA:UniProtKB-EC.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF177; N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF13412; HTH_24; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:CDI40789.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010802};
KW Transferase {ECO:0000313|EMBL:CDI40789.1}.
SQ SEQUENCE 419 AA; 46144 MW; E6E6B31C33033AB0 CRC64;
MIYLAKEPGN SKYVKKLNRM SVINTIKKHE PISRQQLAKV TGLTPPTITG IVRELLDMGI
VKEVGLDKSR GGRRPVKLRF NPDAGYVMGV EVTRFESFTG TADLKNPPTD FRTLNIDMTE
PEIGIKQLSA EIKKIMDEER YIKKTFLGVG VAFPGLLNIC EGSVKRSINL GSSWNNFPVK
EILENELELP VFIENNSNAS ALAERWFGGG ADCKDLVYIN LGEGISAGIV INDRVLQGAQ
GHAGEIGHMS IQEDGPLCNC GNRGCLESIC GIPALVRQAK SELPVIPDDD ALKKAWLANN
EISIEDIIKS ACIKDSYSWE LLRQMSVYVG KAIANVINFY NPKIVFIGGK MSVVADYFMD
VIKQNIDTHA FPEIVLSTDI EISTLKDKSG VMGACALVLK HLFKSNSDML EDVQQASYE
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