ID F4P4I5_BATDJ Unreviewed; 1514 AA.
AC F4P4I5;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=DNA helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=BATDEDRAFT_25649 {ECO:0000313|EMBL:EGF80034.1};
OS Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid
OS fungus).
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC Rhizophydiales incertae sedis; Batrachochytrium.
OX NCBI_TaxID=684364 {ECO:0000313|EMBL:EGF80034.1, ECO:0000313|Proteomes:UP000007241};
RN [1] {ECO:0000313|EMBL:EGF80034.1, ECO:0000313|Proteomes:UP000007241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAM81 / FGSC 10211 {ECO:0000313|Proteomes:UP000007241};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Kuo A., Salamov A., Schmutz J., Lucas S., Pitluck S., Rosenblum E.,
RA Stajich J., Eisen M., Grigoriev I.V.;
RT "The draft genome of Batrachochytrium dendrobatidis.";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; GL882885; EGF80034.1; -; Genomic_DNA.
DR RefSeq; XP_006679497.1; XM_006679434.1.
DR STRING; 684364.F4P4I5; -.
DR GeneID; 18238834; -.
DR HOGENOM; CLU_248045_0_0_1; -.
DR InParanoid; F4P4I5; -.
DR OrthoDB; 5474026at2759; -.
DR Proteomes; UP000007241; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0009378; F:four-way junction helicase activity; IBA:GO_Central.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006268; P:DNA unwinding involved in DNA replication; IBA:GO_Central.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR CDD; cd18018; DEXHc_RecQ4-like; 1.
DR Gene3D; 1.10.10.1460; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF108; ATP-DEPENDENT DNA HELICASE Q4; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007241}.
FT DOMAIN 804..983
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1024..1178
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 169..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 289..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 379..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 655..680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..399
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..680
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1514 AA; 168523 MW; F214924F41481214 CRC64;
MEEYRNQLAD WEQYFCRKYG RKPLPADIDK RPRVAATYRR YQELKNRVNG SNNAQISDTS
TNHFKQLRPL RSISELDSIN SRCTSSSNSQ IKPVVPTTSL DHSSKHCAKS PIHFIKSPFG
SKVDRIAYER MYSENQKPKD TIIHSGPAES TFGLASNINV SIDGIQKDSV FKTPTKPRSN
SNSKSASNTS PLFKSPLSAS RHNHSKSPFL LSSTKSNGLG ATFVKDDMDE EWIGPSPAKT
NRTGQTSLME SLFVTGFEEK LEKSSKKSIS SGGSNLFLDR LSAVKSPKKG LTSVSKSMLH
TSASTTSKRL PRRTQSESIL KKMPAFFKNT SLANFDINSQ VSKTVLPNTV FTAPTSDPSL
PTSIDDINTP FGTFLNKDHQ NTNHQAGEHI EDKKDLPSLP DRNQVLNSST DIAKNDKYKI
QSMFSNGTRS SRWHLQSSLP KPTKGFVSVH STSSIPIYPK EQPALSCSKP YFSHDENDDS
DSSVDFGSNC VVTCPNKFIN ARSLKRQTSK TLLLTSNYRE FLSLKEQQAL ADVIRDVDQI
VTTIPGPSTM SELTVSNQAI SDCHDTFTGM GITFDTFKTA LTPSNVMVVK HDNFLSIQNE
SLATNFDTES SRCIPTLKKE PRLETMNIES VDIESTKGKS RAVDNEVDSA LVPRAKKSRI
TKSKSATESM PSQEKTRKTG TGVVNSNYRA LKLGKKPVNG SSGRKFGHRT GSKRVINDPD
RSREINTFGE IEELDKKSKM TDAIVDEAPV NIPIDFIYTS ATATPSCVPV YHKNGGNLVY
VDLNLALQRL CGLDSFREGQ YEAIARILSG KSTLVVLPTG GGKSLCYQLP AFIIRHIPQA
QPSLILIVSP TISLMRDQMR CLPAGIRAAC LSSGHQSASV TREIYKKLEF NELDIIFVAP
ERLQSASFVE LIQTGKIMPI QIAYIDEAHC LSEWSHNFRP SYLHLHNILK KTLGVECFVA
LSATATLPTR RSICGMLNID QENGCIVSPS IIRNNLNVSV TPVSADDSRD ATLVDMLRTL
PYRNLESIIV YTMFQASHLI PDFWSVTAQA DRVAQYLRVR DFDADAYHAG KTPEQREYVQ
SRFQHGRLRI IVATVAFGLG INKQNVRSVI HYSMPRSIED YMQEIGRSGR NGEPAYCNLF
LVQEDYVKHR SFVFSDGVDE AGIWRLLKVL FPPVKSGKPG AGCRDNRAGS ANVKANDSIR
LILPIQNLES QLDIRESVIS TMLSYIELSD TDNPPIKVFP TLSSTYTLFC SKAKLETLAE
SSDVIRWARV HGSTIKYGLE FDTLKVAESA GVEPSTVATE LWKYQASKEL KFNSGDKAFN
ILVNRAWTDA NEKQAFLDGL CDSLFKKMSA IESASAWKLD YLYETLYAAI RDPLDMDTSL
PSNSITNESE SAANTLAESL PIAQQTLMNS IMLYFQLPEI GKDQLEGDKW GFRDPELIEK
QKLAKINVEI SIKSFVKAHL SEVTSGRAVA RIFHGLSSPK YPAKIWLSNK HWNSHPYYNF
KDLARLASKA MQNR
//
