ID F4PE56_BATDJ Unreviewed; 1407 AA.
AC F4PE56;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
GN ORFNames=BATDEDRAFT_14837 {ECO:0000313|EMBL:EGF76498.1};
OS Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid
OS fungus).
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC Rhizophydiales incertae sedis; Batrachochytrium.
OX NCBI_TaxID=684364 {ECO:0000313|EMBL:EGF76498.1, ECO:0000313|Proteomes:UP000007241};
RN [1] {ECO:0000313|EMBL:EGF76498.1, ECO:0000313|Proteomes:UP000007241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAM81 / FGSC 10211 {ECO:0000313|Proteomes:UP000007241};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Kuo A., Salamov A., Schmutz J., Lucas S., Pitluck S., Rosenblum E.,
RA Stajich J., Eisen M., Grigoriev I.V.;
RT "The draft genome of Batrachochytrium dendrobatidis.";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU004279};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|RuleBase:RU004279}.
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DR EMBL; GL882896; EGF76498.1; -; Genomic_DNA.
DR RefSeq; XP_006682763.1; XM_006682700.1.
DR STRING; 684364.F4PE56; -.
DR GeneID; 18236966; -.
DR HOGENOM; CLU_000487_3_0_1; -.
DR InParanoid; F4PE56; -.
DR OMA; AVCPPYN; -.
DR OrthoDB; 169836at2759; -.
DR Proteomes; UP000007241; Unassembled WGS sequence.
DR GO; GO:0005666; C:RNA polymerase III complex; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006383; P:transcription by RNA polymerase III; IEA:GOC.
DR CDD; cd02736; RNAP_III_Rpc1_C; 1.
DR CDD; cd02583; RNAP_III_RPC1_N; 1.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 1.10.150.390; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR Gene3D; 3.30.1490.180; RNA polymerase ii; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR035698; RNAP_III_Rpc1_C.
DR InterPro; IPR035697; RNAP_III_RPC1_N.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF32; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007241};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279}.
FT DOMAIN 246..551
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
SQ SEQUENCE 1407 AA; 157432 MW; 5792D97E422A9E18 CRC64;
MVELEHRINN VFSRKRIDFG VLSAQDAKQL SILELHQRDL YDVSKNNRPP AKFGALDRRL
GTADKSIPCE TCGETMQDCV GHFGIIRLVL PVFHIGYFKL MITVLQNICK SCSCVLIDEQ
TRRVYLKRLR NPNLDGVRRK DILKNLNILC KKTARCPHCN SLNGMVKKVG ALKIVHEKFK
KKAKTEEEDE FRKSFNHAIK LDPTLKAHIS KAQEDLNPLV IMNLFQAISN DDCELMGLNP
ELSRPEQYIW SALPVPPVCI RPSVGQENSS TEDDLTVLAS EIVDINTKIR ACMLDGTQTP
LLMEYWDFLQ LQCAMYITSD LPGIPTHLQG SLPKIKKGFC QRLKGKHGRF RGNLSGKRVD
FSGRTVISPD PNLRIDQVAV PERVAKVLTY PERVTPYNIE RLRMNVINGP DVHPGATYVA
AQSTGMKKFL KFGNRNRTAD ELQYGDTVER HLQDDDVVLF NRQPSLHKLS IMSHFVKVRP
WRTFRFNECV CTPYNADFDG DEMNLHVPQT EEARAEAMEL MGTKNNLVTP RNGEPLIAAT
QDFITASYLL SRKDVFYDRS QFSQICSYLG DSLLNIDLPP PTILKPFALW TGKQVFGVML
RPSQESKIII NLETKCRTFD KDQKDRHGIA FGKSKTQAGH LFHPSFCPND GYLFFHNSEL
MSGVIDKAII GDGNKKSMFY VVLRDYGPPA AADCMNKIAK LSARWLANQG FSIGINDVQP
GDRLRTEKEI TVEKGYTDCD ETIALSRQNL LPNQPGCNQE QTLESKLSGI LSKIRDDVGQ
VCFQELNKYN APLIMSLCGS KGSKINVSQM VACVGQQIIS GSRIPNGFGD RSLPHFAKNS
KTPPAKGFVG NSFYSGLSPT EFLFHAVSGR EGLVDTAVKT AETGYMQRRL MKALEDLVCH
YDLSVRDSGG GIVQFRYGDD GLDPPNIEGS ELPVEFSRNL MHSRALIPIE NDPFLSRNQW
QKIIQVETNK KEFKTICSSE FIRALVAFLE RELGDVAKPV HGRDTDKYAI KNGVTATQLY
HFINTCKTKY IRAVVQPGTA VGAVGAQSIG EPGTQMTLKT FHFAGVASMN ITLGVPRIKE
IINASKTIST PIIDAKLAPM VGGYGGNQTR FAAEAASRVV KGRIEKTLLE DITEYIQEVI
TPEEVCIVIK IDLETIRKLQ LEVNIDTIRW AIIRAPKLKI SDMVTISDRL RVVVPRLKND
SINSYIIMQA LKRALPKVVV KGLSTVSRAV INDVTEESRF NLLVEGYGLK EVMGIDGVDG
LNTSSNHVLE CLKTLGIEAA RQTIIDQILY TMKSHGMTID RRHVMLLADL MSFKGEVLGI
TRFGIAKMKD SVLMLASFEK TTDHLFEASF YSKHDKIQGV SECIIMGVPM SLGTGLFKLV
QETNQFVKTK QPLLFDAPDF HSPLFSV
//
