ID F4RHV0_MELLP Unreviewed; 529 AA.
AC F4RHV0;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Nodulin-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MELLADRAFT_77446 {ECO:0000313|EMBL:EGG08069.1};
OS Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7) (Poplar leaf
OS rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Melampsoraceae; Melampsora.
OX NCBI_TaxID=747676 {ECO:0000313|Proteomes:UP000001072};
RN [1] {ECO:0000313|Proteomes:UP000001072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=98AG31 / pathotype 3-4-7 {ECO:0000313|Proteomes:UP000001072};
RX PubMed=21536894; DOI=10.1073/pnas.1019315108;
RA Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E.,
RA Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J., Cantarel B.L.,
RA Chiu R., Coutinho P.M., Feau N., Field M., Frey P., Gelhaye E.,
RA Goldberg J., Grabherr M.G., Kodira C.D., Kohler A., Kuees U.,
RA Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E., Murat C.,
RA Pangilinan J.L., Park R., Pearson M., Quesneville H., Rouhier N.,
RA Sakthikumar S., Salamov A.A., Schmutz J., Selles B., Shapiro H.,
RA Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y., Rouze P.,
RA Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C.,
RA Grigoriev I.V., Szabo L.J., Martin F.;
RT "Obligate biotrophy features unraveled by the genomic analysis of rust
RT fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GL883102; EGG08069.1; -; Genomic_DNA.
DR RefSeq; XP_007408834.1; XM_007408772.1.
DR AlphaFoldDB; F4RHV0; -.
DR EnsemblFungi; EGG08069; EGG08069; MELLADRAFT_77446.
DR GeneID; 18932947; -.
DR KEGG; mlr:MELLADRAFT_77446; -.
DR VEuPathDB; FungiDB:MELLADRAFT_77446; -.
DR eggNOG; ENOG502RWDV; Eukaryota.
DR HOGENOM; CLU_012596_1_0_1; -.
DR InParanoid; F4RHV0; -.
DR OrthoDB; 1096898at2759; -.
DR Proteomes; UP000001072; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR21576:SF158; NODULIN-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR21576; UNCHARACTERIZED NODULIN-LIKE PROTEIN; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001072};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 425..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 473..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 222..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..253
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..529
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 529 AA; 57511 MW; 6D8E3075C5162DAB CRC64;
MTTHSQEFNS TRIIILISSI IVSLSAGTNY AFSAYSPQLA ERLKLSSTTL NAIGISGNIG
MYFASPIVGG IIDRIGPRKP LLFASGLLFL GYGIVWEIFR SNPIPSSDQD QKLIKSNPIT
VAILAFGMLL TGIGSSTALS SAAGAAAKSF HSRIRATVIG FTLAGFGLSA FFWTRIGALF
FSDDTSSFLL VLSLGTSSFI LIGVCGLSSL DTLEQERRPK IESLADDEQE SSAIATSSHQ
DLSPSQDQEH TTQETIQSID EKVDVYGTKL MKTLDFWLLW IVMGCCCGTA LMIINNIGTM
IATLDFQEHP PTSTHPSDPN NSSIVSHIQS NQVSLLSVFN CLGRIFAGLI SDTLEARYGL
SKVWWLCWVS SLFLLSQYLG QQVVKNLSSI SLLTGLTGFA YGNMYGSGPN LMIIWFGVDH
FTTNFGFLNL APVFAGQIIN LSFGQIYDAH YRQNPLPNQL LCMEGQACYR DAFRITIVSC
GIALFLAGVL VLRNRNGNGN RLHKRKLSGS DEETSTEQTW MLGSPTLTA
//
