ID F4T7N9_ECOLX Unreviewed; 188 AA.
AC F4T7N9;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=DNA replication protein DnaC {ECO:0000256|ARBA:ARBA00039766};
DE Flags: Fragment;
GN ORFNames=ECIG_04664 {ECO:0000313|EMBL:EGI13316.1};
OS Escherichia coli M605.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=656417 {ECO:0000313|EMBL:EGI13316.1, ECO:0000313|Proteomes:UP000004710};
RN [1] {ECO:0000313|EMBL:EGI13316.1, ECO:0000313|Proteomes:UP000004710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M605 {ECO:0000313|EMBL:EGI13316.1,
RC ECO:0000313|Proteomes:UP000004710};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Feldgarden M., Gordon D.M., Johnson J.R., Johnston B.D., Young S., Zeng Q.,
RA Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Escherichia coli M605.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is required for chromosomal replication. It
CC forms, in concert with DnaB protein and other prepriming proteins DnaT,
CC N, N', N'' a prepriming protein complex on the specific site of the
CC template DNA recognized by protein N'. {ECO:0000256|ARBA:ARBA00037642}.
CC -!- SIMILARITY: Belongs to the DnaC family.
CC {ECO:0000256|ARBA:ARBA00038338}.
CC -!- SIMILARITY: Belongs to the IS21/IS1162 putative ATP-binding protein
CC family. {ECO:0000256|ARBA:ARBA00008059}.
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DR EMBL; GL883931; EGI13316.1; -; Genomic_DNA.
DR RefSeq; WP_000618769.1; NZ_GL883931.1.
DR AlphaFoldDB; F4T7N9; -.
DR HOGENOM; CLU_1247665_0_0_6; -.
DR Proteomes; UP000004710; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR047661; IstB.
DR InterPro; IPR002611; IstB_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; NF038214; IS21_help_AAA; 1.
DR PANTHER; PTHR30050; CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA; 1.
DR PANTHER; PTHR30050:SF9; DNA REPLICATION PROTEIN DNAC; 1.
DR Pfam; PF01695; IstB_IS21; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT DOMAIN 30..164
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EGI13316.1"
SQ SEQUENCE 188 AA; 21074 MW; 02DE7247ACE4C280 CRC64;
KTFEEYDFTF ATGAPQKQLQ SLRSLSFIER NENIVLLGPS GVGKTHLAIA MGYEAVRAGI
KVRFTTAADL LLQLSTAQRQ GRYKTTLQRG VMAPRLLIID EIGYLPFSQE EAKLFFQVIA
KRYEKSAMIL TSNLPFGQWD QTFAGDAALT SAMLDRILHH SHVVQIKGES YRLRQKRKAG
VIAEANPE
//
