ID F4TG76_ECOLX Unreviewed; 699 AA.
AC F4TG76;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Phage terminase large subunit (GpA) {ECO:0000313|EMBL:EGI21094.1};
GN ORFNames=ECJG_02469 {ECO:0000313|EMBL:EGI21094.1};
OS Escherichia coli M718.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=656419 {ECO:0000313|EMBL:EGI21094.1, ECO:0000313|Proteomes:UP000002790};
RN [1] {ECO:0000313|EMBL:EGI21094.1, ECO:0000313|Proteomes:UP000002790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M718 {ECO:0000313|EMBL:EGI21094.1,
RC ECO:0000313|Proteomes:UP000002790};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Feldgarden M., Gordon D.M., Johnson J.R., Johnston B.D., Young S., Zeng Q.,
RA Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Escherichia coli M718.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL884125; EGI21094.1; -; Genomic_DNA.
DR RefSeq; WP_000507036.1; NZ_GL884125.1.
DR AlphaFoldDB; F4TG76; -.
DR HOGENOM; CLU_023850_0_1_6; -.
DR Proteomes; UP000002790; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR HAMAP; MF_04144; TERL_LAMBDA; 1.
DR InterPro; IPR046453; GpA_ATPase.
DR InterPro; IPR046454; GpA_endonuclease.
DR InterPro; IPR008866; Phage_lambda_GpA-like.
DR PANTHER; PTHR34413:SF2; PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED; 1.
DR PANTHER; PTHR34413; PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED-RELATED; 1.
DR Pfam; PF05876; GpA_ATPase; 1.
DR Pfam; PF20454; GpA_nuclease; 1.
PE 3: Inferred from homology;
FT DOMAIN 40..303
FT /note="Phage terminase large subunit GpA ATPase"
FT /evidence="ECO:0000259|Pfam:PF05876"
FT DOMAIN 325..643
FT /note="Terminase large subunit GpA endonuclease"
FT /evidence="ECO:0000259|Pfam:PF20454"
FT REGION 660..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..674
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 79271 MW; 57F5032B4B0FD604 CRC64;
MGFSSARNLG RDISAGFSPP RRMPISEAVK KFMRVPKGAG NSVPWDPELT PYIIEPMNCL
ASREYDAVIF VGPARTGKTI GLIDGWIVYT IVCDPSDMLV VQMTEDKARE HSKKRLDRTF
RSSAAVKKRM SPRRNDNNVH DKTFRDGSFL KIGWPSVNIM SSSDYRFVAL TDYDRFPENI
DSEGDGFSLA SKRTTTFMSA GMTLVESSPG RDICDSKWRR KSPHEAPPTT GILSLYNRGD
RRRWYWSCPH CGEYFQPAMD AMTGYRNEPD PFKASEAAYL LCPHCSGIIT AEKKRELNSA
GVWLREGQVI DRNGNVSGEP RRSRIASFWM EGPAAAYQTW AQLVYKLLTA EQEYEATGSE
ETLRAVINTD WGLPYLPRAS MEQRKSELLE QRAEPVPSRS VPDGVNFLVA TVDVQAGRHR
RFVVQVTGYG SRGERWIIDR YNITQSLRSD CDGESQRIDP ASYPEDWDVL LTDVFHKSWP
LASDPSQQMR LMAMAVDSGG EDGVTDNAYK FWRRCRRDGL GKRIYLFKGD SIRRAKLISR
TFPDNTGRTG RRAQAAGDVP LWLLQTDALK DRVNNALWRD SPGPGYVHFP DWLGSWFYDE
LTYEERSSDG KWSKPGRGAN EAFDLMVYAE ALVILHGYEK IRWPDAPEWA SRETWLECVQ
DSTEPSSSPE PVSTPVKKQK RKKTVTDDVN PWLTSGGWL
//
