ID F4TIB4_ECOLX Unreviewed; 239 AA.
AC F4TIB4;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Protein SanA {ECO:0000313|EMBL:EGI20498.1};
GN ORFNames=ECJG_01880 {ECO:0000313|EMBL:EGI20498.1};
OS Escherichia coli M718.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=656419 {ECO:0000313|EMBL:EGI20498.1, ECO:0000313|Proteomes:UP000002790};
RN [1] {ECO:0000313|EMBL:EGI20498.1, ECO:0000313|Proteomes:UP000002790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M718 {ECO:0000313|EMBL:EGI20498.1,
RC ECO:0000313|Proteomes:UP000002790};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Feldgarden M., Gordon D.M., Johnson J.R., Johnston B.D., Young S., Zeng Q.,
RA Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Escherichia coli M718.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Participates in the barrier function of the cell envelope.
CC {ECO:0000256|ARBA:ARBA00037355}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004377}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004377}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; GL884129; EGI20498.1; -; Genomic_DNA.
DR RefSeq; WP_000920064.1; NZ_GL884129.1.
DR AlphaFoldDB; F4TIB4; -.
DR GeneID; 75206397; -.
DR HOGENOM; CLU_051474_0_2_6; -.
DR Proteomes; UP000002790; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd06259; YdcF-like; 1.
DR InterPro; IPR003848; DUF218.
DR InterPro; IPR023604; Uncharacterised_SanA.
DR PANTHER; PTHR30336; INNER MEMBRANE PROTEIN, PROBABLE PERMEASE; 1.
DR PANTHER; PTHR30336:SF0; PROTEIN SANA; 1.
DR Pfam; PF02698; DUF218; 1.
DR PIRSF; PIRSF005011; SanA; 1.
PE 4: Predicted;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 47..170
FT /note="DUF218"
FT /evidence="ECO:0000259|Pfam:PF02698"
SQ SEQUENCE 239 AA; 27287 MW; 574EF9B02249547C CRC64;
MLKRVFLSLL VLIGLLLLTV LGLDRWMSWK TAPYIYDELQ DLPYRQVGVV LGTAKYYRTG
VINQYYRYRI QGAINAYNSG KVNYLLLSGD NALQSYNEPM TMRKDLIAAG VDPSDIVLDY
AGFRTLDSIV RTRKVFDTND FIIITQRFHC ERALFIALHM GIQAQCYAVP SPKDMLSVRI
REFAARFGAL ADLYIFKREP RFLGPLVPIP AMHQVPEDAQ GYPAVTPEQL LELQKKQGK
//
