ID   F4UXC6_ECOLX            Unreviewed;       336 AA.
AC   F4UXC6;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Oxidoreductase, aldo/keto reductase family {ECO:0000313|EMBL:EGI42715.1};
GN   ORFNames=ECNG_01484 {ECO:0000313|EMBL:EGI42715.1};
OS   Escherichia coli TA280.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=656444 {ECO:0000313|EMBL:EGI42715.1, ECO:0000313|Proteomes:UP000004877};
RN   [1] {ECO:0000313|EMBL:EGI42715.1, ECO:0000313|Proteomes:UP000004877}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TA280 {ECO:0000313|EMBL:EGI42715.1,
RC   ECO:0000313|Proteomes:UP000004877};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Feldgarden M., Gordon D.M., Johnson J.R., Johnston B.D., Young S., Zeng Q.,
RA   Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA   Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA   Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Escherichia coli TA280.";
RL   Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL884332; EGI42715.1; -; Genomic_DNA.
DR   AlphaFoldDB; F4UXC6; -.
DR   HOGENOM; CLU_023205_5_0_6; -.
DR   Proteomes; UP000004877; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd19152; AKR_AKR15A; 1.
DR   Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR   InterPro; IPR020471; AKR.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   PANTHER; PTHR42686:SF1; ALDO_KET_RED DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR42686; GH17980P-RELATED; 1.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE   4: Predicted;
FT   DOMAIN          10..322
FT                   /note="NADP-dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00248"
SQ   SEQUENCE   336 AA;  36916 MW;  5E6C92F98969640A CRC64;
     MSIKNLLPGK IGLGGAPLGN MFRAIPEDEA HATVSEAWNL GVRYFDTAPL YGSGLSEIRM
     GEALSQYPRD EYVLSSKVGR IMLDEMEDPA KRDFGEKGGL FEHGLKNKIL NDYSADATLR
     SIEDSLKRLK TDRLDIVWIH DPAQDFYGDS WLEQFNIART GAFRALTRLR DEGVIKAWGL
     GVNRVEPCEL TLALDEPKPD AFLLAGRYSL LDHERALQRL MPEALEQNVD IVVGGPYSSG
     VLAGGEHFEY QKASAAIQQK VAQINTIATR FNVNVKAAAL QFALANPAVA AVIPGSSRPG
     RMAEDLAALN APVPAEFWAE MRRQNLVAEN APLPTR
//