ID F4V5I8_ECOLX Unreviewed; 255 AA.
AC F4V5I8;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Type III secretion apparatus protein SpaR/YscT/HrcT {ECO:0000313|EMBL:EGI39829.1};
GN ORFNames=ECNG_00889 {ECO:0000313|EMBL:EGI39829.1};
OS Escherichia coli TA280.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=656444 {ECO:0000313|EMBL:EGI39829.1, ECO:0000313|Proteomes:UP000004877};
RN [1] {ECO:0000313|EMBL:EGI39829.1, ECO:0000313|Proteomes:UP000004877}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TA280 {ECO:0000313|EMBL:EGI39829.1,
RC ECO:0000313|Proteomes:UP000004877};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Feldgarden M., Gordon D.M., Johnson J.R., Johnston B.D., Young S., Zeng Q.,
RA Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Escherichia coli TA280.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|RuleBase:RU362072}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU362072}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FliR/MopE/SpaR family.
CC {ECO:0000256|ARBA:ARBA00009772, ECO:0000256|RuleBase:RU362072}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362072}.
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DR EMBL; GL884370; EGI39829.1; -; Genomic_DNA.
DR AlphaFoldDB; F4V5I8; -.
DR HOGENOM; CLU_063626_0_3_6; -.
DR Proteomes; UP000004877; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR InterPro; IPR002010; T3SS_IM_R.
DR InterPro; IPR006304; T3SS_SpaR/YscT.
DR NCBIfam; TIGR01401; fliR_like_III; 1.
DR PANTHER; PTHR30065; FLAGELLAR BIOSYNTHETIC PROTEIN FLIR; 1.
DR PANTHER; PTHR30065:SF1; SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAR; 1.
DR Pfam; PF01311; Bac_export_1; 1.
DR PRINTS; PR00953; TYPE3IMRPROT.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU362072};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362072};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362072};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362072}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362072"
FT TRANSMEM 78..102
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362072"
FT TRANSMEM 182..203
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362072"
FT TRANSMEM 209..231
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362072"
SQ SEQUENCE 255 AA; 28154 MW; 12A2E2E19C3CD0E4 CRC64;
MGEAMLYQLH SLLAATALGF CRLAPTFYLL PFFASGNIPT VVRHPIIIVV SCALVQHYHY
ELSTLNEIDI ALFAAREIII GLFIACLLAS PFWIFLAIGS FIDNQRGATL SSTLDPATGV
DTSELARLFN LFSAAVYLTN GGLNFILETL WQSYNLWPSG NFNFPKLEPL FSYINNIMTH
TIVYASPVIA VMLGGEAVLG LLARYASQLN AFAISLTVKS ALAFLILIIY FGPILAERVM
PLSFFPEQLQ LYIDK
//
