ID   F4V5R3_ECOLX            Unreviewed;       425 AA.
AC   F4V5R3;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Putative oxidoreductase {ECO:0000313|EMBL:EGI39904.1};
GN   ORFNames=ECNG_00972 {ECO:0000313|EMBL:EGI39904.1};
OS   Escherichia coli TA280.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=656444 {ECO:0000313|EMBL:EGI39904.1, ECO:0000313|Proteomes:UP000004877};
RN   [1] {ECO:0000313|EMBL:EGI39904.1, ECO:0000313|Proteomes:UP000004877}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TA280 {ECO:0000313|EMBL:EGI39904.1,
RC   ECO:0000313|Proteomes:UP000004877};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Feldgarden M., Gordon D.M., Johnson J.R., Johnston B.D., Young S., Zeng Q.,
RA   Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA   Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA   Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Escherichia coli TA280.";
RL   Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL884370; EGI39904.1; -; Genomic_DNA.
DR   AlphaFoldDB; F4V5R3; -.
DR   HOGENOM; CLU_054732_0_0_6; -.
DR   Proteomes; UP000004877; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd08238; sorbose_phosphate_red; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR   PANTHER; PTHR43401:SF2; L-THREONINE 3-DEHYDROGENASE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          27..97
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          186..329
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   425 AA;  45924 MW;  6F7962C2709B8985 CRC64;
     MKTKVAAIYG KRDVRLREFE LPEITDNELL VSVISDSVCL STWKAALLGS EHKRVPDDLE
     NHPVITGHEC AGVIVEVGKN LTGKYKKGQR FVLQPAMGLP SGYSAGYSYE YFGGNATYMI
     IPEIAINLGC VLPYHGSYFA AASLAEPMCC IIGAYHANYH TTQYVYEHRM GVKPGGNIAL
     LACAGPMGIG AIDYAINGGI QPSRVVVVDI DDKRLAQVQK LLPVELAASK GIELVYMNTK
     GMSDPVQTLR ALTDDAGFDD VFVYAAVPAV VEMADELLAE DGCLNFFAGP TDKNFKVPFN
     FYNVHYNSTH VVGTSGGSTD DMKEAITLSA TGQLQPSFMV THIGGLDAVP ETVLNLPDIP
     GGKKLIYNGV TMPLTAIADF AEKGKTDPLF KELARLVEET HGIWNEQAEK YLLAQFGVDI
     GEAAQ
//