ID F4VF56_ECOLX Unreviewed; 349 AA.
AC F4VF56;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Hypothetical tRNA/rRNA methyltransferase YfiF {ECO:0000313|EMBL:EGI46358.1};
GN ORFNames=ECPG_01253 {ECO:0000313|EMBL:EGI46358.1};
OS Escherichia coli H591.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=656408 {ECO:0000313|EMBL:EGI46358.1, ECO:0000313|Proteomes:UP000004681};
RN [1] {ECO:0000313|EMBL:EGI46358.1, ECO:0000313|Proteomes:UP000004681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H591 {ECO:0000313|EMBL:EGI46358.1,
RC ECO:0000313|Proteomes:UP000004681};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Feldgarden M., Gordon D.M., Johnson J.R., Johnston B.D., Young S., Zeng Q.,
RA Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Escherichia coli H591.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL884455; EGI46358.1; -; Genomic_DNA.
DR AlphaFoldDB; F4VF56; -.
DR HOGENOM; CLU_021322_2_1_6; -.
DR Proteomes; UP000004681; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18095; SpoU-like_rRNA-MTase; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR013123; SpoU_subst-bd.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR InterPro; IPR016479; YfiF_prd.
DR PANTHER; PTHR46429; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR PANTHER; PTHR46429:SF2; TRNA_RRNA METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR Pfam; PF08032; SpoU_sub_bind; 1.
DR PIRSF; PIRSF006280; YfiF_prd; 1.
DR SMART; SM00967; SpoU_sub_bind; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EGI46358.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EGI46358.1}.
FT DOMAIN 113..188
FT /note="RNA 2-O ribose methyltransferase substrate binding"
FT /evidence="ECO:0000259|SMART:SM00967"
FT REGION 1..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..73
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 349 AA; 38266 MW; 23164DCAAE090C48 CRC64;
MEKSMNDEMK GKSGKVKVMY VRSDDDSDKR THNSRTGKGG GRPGKSRADG GRRPARDDKQ
SQPRDRKWED SPWRTVSRAP GDETPEKADH GGISGKSYID PEVLRRQRAE ETRVYGENAC
QALFQSRPEA IVRAWFIQSV TPRFKEALRW MAANRKAYHV VDEAELTKAS GTEHHGGVCF
LIKKRNGTTV QQWVSQAGAQ DCVLALENES NPHNLGGMMR SCAHFGVKGV VVQDAALLES
GAAIRTAEGG AEHVQPITGD NIVNVLDDFR QAGYTVVTTS SEQGKPLFKT SLPAKMVLVL
GQEYEGLPDA ARDPNDLRVK IDGTGNVAGL NISVATGVLL GEWWRQNKA
//
