GenomeNet

Database: UniProt
Entry: F4W7K3_ACREC
LinkDB: F4W7K3_ACREC
Original site: F4W7K3_ACREC 
ID   F4W7K3_ACREC            Unreviewed;      2004 AA.
AC   F4W7K3;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   25-OCT-2017, entry version 33.
DE   RecName: Full=Sodium channel protein {ECO:0000256|RuleBase:RU361132};
GN   ORFNames=G5I_01419 {ECO:0000313|EMBL:EGI69876.1};
OS   Acromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex
OS   octospinosus echinatior).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Hymenoptera; Apocrita; Aculeata;
OC   Vespoidea; Formicidae; Myrmicinae; Acromyrmex.
OX   NCBI_TaxID=103372 {ECO:0000313|Proteomes:UP000007755};
RN   [1] {ECO:0000313|Proteomes:UP000007755}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21719571; DOI=10.1101/gr.121392.111;
RA   Nygaard S., Zhang G., Schiott M., Li C., Wurm Y., Hu H., Zhou J.,
RA   Ji L., Qiu F., Rasmussen M., Pan H., Hauser F., Krogh A.,
RA   Grimmelikhuijzen C.J., Wang J., Boomsma J.J.;
RT   "The genome of the leaf-cutting ant Acromyrmex echinatior suggests key
RT   adaptations to advanced social life and fungus farming.";
RL   Genome Res. 0:0-0(2011).
CC   -!- FUNCTION: Mediates the voltage-dependent sodium ion permeability
CC       of excitable membranes. {ECO:0000256|RuleBase:RU361132}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU361132}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- SIMILARITY: Belongs to the sodium channel (TC 1.A.1.10) family.
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361132}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; GL887844; EGI69876.1; -; Genomic_DNA.
DR   InParanoid; F4W7K3; -.
DR   Proteomes; UP000007755; Unassembled WGS sequence.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   InterPro; IPR031649; GPHH_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR001696; Na_channel_asu.
DR   Pfam; PF16905; GPHH; 1.
DR   Pfam; PF00520; Ion_trans; 4.
DR   PRINTS; PR00170; NACHANNEL.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007755};
KW   Ion channel {ECO:0000256|RuleBase:RU361132,
KW   ECO:0000313|EMBL:EGI69876.1};
KW   Ion transport {ECO:0000256|RuleBase:RU361132};
KW   Membrane {ECO:0000256|RuleBase:RU361132};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007755};
KW   Sodium {ECO:0000256|RuleBase:RU361132};
KW   Sodium channel {ECO:0000256|RuleBase:RU361132};
KW   Sodium transport {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361132};
KW   Transport {ECO:0000256|RuleBase:RU361132};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM     47     65       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM     72     90       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    110    130       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    165    185       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    290    316       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    699    730       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    788    813       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1100   1122       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1128   1150       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1182   1208       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1300   1324       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1386   1406       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1412   1433       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1445   1464       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1484   1512       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1582   1606       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   DOMAIN       45    321       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      590    820       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1067   1333       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1385   1618       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1624   1685       GPHH. {ECO:0000259|Pfam:PF16905}.
SQ   SEQUENCE   2004 AA;  229288 MW;  565AD04195961B7A CRC64;
     MFQTFCVVSK RFRKNYIHRF TATNSWFIFS PWNPIRRCCI FLSTNQYFDY VVMATILLNC
     VFLAMTETFD DAELIFLAIY TAEMVIKSIA KGFILNKYTY LRNPWNWLDF VVITSGYATI
     GMAVGNLAGL RTFRVLRALK TVSIMPGLKT IINALLHSFK QLAEVMTLTI FCLMVFALFA
     LQVYMGELRN KCVKQQEPNT TQIDWREWTW NSSNWAFNED EEPIICGNVT GARHCNESYT
     CLCVGPNPNH GYTNFDNFLW SMLTTFQLIT LDYWEDVYNK VLSACGPISV TFFTVVVFFG
     SFYLLNLMLA VVALSYEEEA EITNEERRKD LTDHREDSTF SFDPSKINIK TLTKNKQKRI
     DARKGVLLSS YTRKKTRRRK RGRSSIGQEK NGGARSRSMT PSPSPSPRHS SVRPSHLPLQ
     NISPRPLEPN TVHRLAPNRG MLHSRQASNN SNQQSSLDDS GVVDDHDGDD VTSAEEHDKR
     ELREHRVEKS QEKSPKEHGR IQPIQQMRPD CPPAPVTVSV RTGNREIRVL KCNGVKTKKH
     MYALPPEYLS HIVVLDDLPD RNCDKCIQCC VDYEGWLRFQ NCLYKVVRDP LFELMITLCI
     VLNTGFLAME HHGMSESIRQ ALNIGNKVFT SIFTFECFLK LLALSKDFFN NGWNNFDLII
     VSASLIDLTF ELVDGLSVIR GLRLLRVLKL AQSWTTMKVL LSIIISTIGA LGNLTFVLVI
     VIYIFAVIGM QLFSKDYTLD KFYPDPVPRW NFNDFFHSFM MIFRILCGEW IEPLWDCMRA
     ERDDGPGTCF AIFLPALVMG NFMVLNLFLA LLLNSFNSEE LKQKKEEVGE ESKLARSFDR
     IRSIVRKQKH RKENSENEKN IRLEQIVREV MDKSDKEKYA IQETVLSLPK DNIYNRSYQE
     SLNQPVFTYD PIYRQATLTT YSQSNQETVK ENKKLTEKGN SNETNPEESI ELEVLKDVNP
     DEEVAMLPEE KLAIRNDENI GKRPWHALVS YVDELTVGGR RDSKGRYIDG MGSFPGFGRN
     KKNKEPLDCF PQHFYQKCSC INRCLATDLG KKWIRIRTVV LSVVDTPAFE WMILVLIFAS
     SITLCFEDIY LDDNPFLKKI LYWTNLGFCA LFSVEMLLKW LALGFCKYFT SFWTILDFII
     VFVSMFSLLI EENENLKVLR SLRTLRALRP LRAISRWQGM RIVVNALMYA IPSIFNVLLV
     CLVFWLIFSI MGVQFFGGKF FKCVDEYGEM LDISIVNTKE ECFSKNYSWQ NSKITFDHVG
     IAYLALFQVA TFEGWMEVME DAVDARGVDL QPQREANLYA YLYFVIFIVC GSFFTLNLFI
     GVIIDNFNML KKKYEGGVLE MFLTESQKHY YTAMKKLGRK KPQKVIKRPM NQFLAMFYDL
     SNSRRFEIAI FVLIFLNMLT MGIEHYNQPH PIFFVLEVSN AFFTTVFGLE AIVKIIGLRY
     HYFTVPWNLF DFLLVLASIL GILMEDIMMD FPRLIKAAKG IRKLLFALVV SLPALFNIGA
     LLALITFIYA IIGMSVFGHV RKQGALDDMV NFETFGRSMQ LLFRLMTSAG WNDVLESLMV
     QPPECDPTPN SRQMNGDCGY PLLAITYFTS FIIISYMIVI NMYIAIILEN FNQAHQEEEI
     GIVEDDLEMF YIRWSKYDPH ATQFISFSQL SDFIASLDPP LGISKPNVVA LVSFNLPIAK
     GNKIHCLDIL HALVKHVLGH VEESDDFRKL QEQMDVKFKK QFPTRKELEI VSSTRIWKRQ
     DKAARLIQRS IREYIAMKKE RERIAQEVDS QTQTSSPGGV DGRSGSGWGG KLSALLHVHR
     GSRASSRKSS RASDASDLSE LGTASAWLFP NLPLLLLSGA TGTHEDLPPP ALTVSRPSPT
     ADQPSAASSS GSDSHITVRS LGPTLGRQDA VEKYPEDDVL SPPTSKRSSL RPSGTTLSLN
     TLQRDIKEAF NRRCGSLRRR TPPPEPVQLP VESSDVSILV TEPSPENTAP PSRPPLIRQQ
     SEATVVHVLV HRESEEYQDT PDDS
//
DBGET integrated database retrieval system