ID   F4WSS3_ACREC            Unreviewed;       517 AA.
AC   F4WSS3;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=H/ACA ribonucleoprotein complex subunit 4 {ECO:0000313|EMBL:EGI62730.1};
GN   ORFNames=G5I_08900 {ECO:0000313|EMBL:EGI62730.1};
OS   Acromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex octospinosus
OS   echinatior).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Acromyrmex.
OX   NCBI_TaxID=103372 {ECO:0000313|Proteomes:UP000007755};
RN   [1] {ECO:0000313|EMBL:EGI62730.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Nygaard S., Zhang G.;
RT   "The genome of the leaf-cutting ant Acromyrmex echinatior suggests key
RT   adaptations to social evolution and fungus farming.";
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the pseudouridine synthase TruB family.
CC       {ECO:0000256|ARBA:ARBA00008999}.
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DR   EMBL; GL888327; EGI62730.1; -; Genomic_DNA.
DR   RefSeq; XP_011058988.1; XM_011060686.1.
DR   AlphaFoldDB; F4WSS3; -.
DR   STRING; 103372.F4WSS3; -.
DR   EnsemblMetazoa; XM_011060686.1; XP_011058988.1; LOC105148770.
DR   GeneID; 105148770; -.
DR   KEGG; aec:105148770; -.
DR   eggNOG; KOG2529; Eukaryota.
DR   InParanoid; F4WSS3; -.
DR   OrthoDB; 5472308at2759; -.
DR   Proteomes; UP000007755; Unassembled WGS sequence.
DR   GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd02572; PseudoU_synth_hDyskerin; 1.
DR   CDD; cd21148; PUA_Cbf5; 1.
DR   Gene3D; 3.30.2350.10; Pseudouridine synthase; 1.
DR   Gene3D; 2.30.130.10; PUA domain; 1.
DR   InterPro; IPR012960; Dyskerin-like.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR   InterPro; IPR002501; PsdUridine_synth_N.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR004802; tRNA_PsdUridine_synth_B_fam.
DR   InterPro; IPR032819; TruB_C.
DR   InterPro; IPR004521; Uncharacterised_CHP00451.
DR   NCBIfam; TIGR00425; CBF5; 1.
DR   NCBIfam; TIGR00451; unchar_dom_2; 1.
DR   PANTHER; PTHR23127; CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5; 1.
DR   PANTHER; PTHR23127:SF0; H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1; 1.
DR   Pfam; PF08068; DKCLD; 1.
DR   Pfam; PF01472; PUA; 1.
DR   Pfam; PF16198; TruB_C_2; 1.
DR   Pfam; PF01509; TruB_N; 1.
DR   SMART; SM01136; DKCLD; 1.
DR   SMART; SM00359; PUA; 1.
DR   SUPFAM; SSF55120; Pseudouridine synthase; 1.
DR   SUPFAM; SSF88697; PUA domain-like; 1.
DR   PROSITE; PS50890; PUA; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007755};
KW   Ribonucleoprotein {ECO:0000313|EMBL:EGI62730.1}.
FT   DOMAIN          35..93
FT                   /note="Dyskerin-like"
FT                   /evidence="ECO:0000259|SMART:SM01136"
FT   DOMAIN          284..358
FT                   /note="PUA"
FT                   /evidence="ECO:0000259|SMART:SM00359"
FT   REGION          387..517
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        397..427
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        429..445
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   517 AA;  58573 MW;  17FB2F99B841270D CRC64;
     MEEDKNKKKD KKSIGELQLT TKCEIDPSKM EVKLECKDWP LLFKNFDKML TRTKHFTPLT
     SGSTPLNRSL SEYIKSGCIN LDKPCNPSSH EVVAWIKKIL RVEKTGHSGT LDPKVSGCLI
     VCIDRATRLA KSQQSAGKEY VAVFKLHSAA ESVQKVNQAL EKLRGALFQR PPLISAVKRQ
     LRVRTVYDSW FLDYDQERNM GIFRVSCEAG SYIRTMCVHL GLFLGTGCHM QELRRSRSGV
     LSEQDGMVTM QDILDAQWLY DNHGDESYLR RVIRPLESLL INHKRIIIKD SAVNAICYGA
     KIMLPGVLMY DQGIELNEEI VIVTTKGEAV AIAIALMSSP TMAACDHGVA AKLKRVIMER
     DSYPRKWGLG PKASQKKRMV AEGLLDKYGK PNEKTPPEWS HSYQDYQNLT TPSTTTASTT
     ASTTEKNGDI VIGKKRKRED TITMDEVQQE TSEILETSSL KEKKKKKEKK KKKEKRDTED
     EVVMEEVTSG ESLAKEEKKK KKKKKKDKDQ DQELMSS
//