ID F4XYJ5_9CYAN Unreviewed; 1072 AA.
AC F4XYJ5;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00022419, ECO:0000256|HAMAP-Rule:MF_00595};
DE Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305, ECO:0000256|HAMAP-Rule:MF_00595};
GN Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595};
GN ORFNames=LYNGBM3L_51900 {ECO:0000313|EMBL:EGJ30408.1};
OS Moorena producens 3L.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Moorena.
OX NCBI_TaxID=489825 {ECO:0000313|EMBL:EGJ30408.1, ECO:0000313|Proteomes:UP000003959};
RN [1] {ECO:0000313|Proteomes:UP000003959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3L {ECO:0000313|Proteomes:UP000003959};
RX PubMed=21555588; DOI=10.1073/pnas.1101137108;
RA Jones A.C., Monroe E.A., Podell S., Hess W.R., Klages S., Esquenazi E.,
RA Niessen S., Hoover H., Rothmann M., Lasken R.S., Yates J.R.III.,
RA Reinhardt R., Kube M., Burkart M.D., Allen E.E., Dorrestein P.C.,
RA Gerwick W.H., Gerwick L.;
RT "Genomic insights into the physiology and ecology of the marine filamentous
RT cyanobacterium Lyngbya majuscula.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:8815-8820(2011).
CC -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC for the tricarboxylic acid cycle. {ECO:0000256|ARBA:ARBA00003670,
CC ECO:0000256|HAMAP-Rule:MF_00595}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC Evidence={ECO:0000256|ARBA:ARBA00001071, ECO:0000256|HAMAP-
CC Rule:MF_00595};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946,
CC ECO:0000256|HAMAP-Rule:MF_00595};
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC {ECO:0000256|ARBA:ARBA00008346, ECO:0000256|HAMAP-Rule:MF_00595}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL890954; EGJ30408.1; -; Genomic_DNA.
DR RefSeq; WP_008188014.1; NZ_MKZR01000001.1.
DR AlphaFoldDB; F4XYJ5; -.
DR eggNOG; COG2352; Bacteria.
DR HOGENOM; CLU_006557_2_0_3; -.
DR OrthoDB; 9768133at2; -.
DR Proteomes; UP000003959; Unassembled WGS sequence.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR HAMAP; MF_00595; PEPcase_type1; 1.
DR InterPro; IPR021135; PEP_COase.
DR InterPro; IPR022805; PEP_COase_bac/pln-type.
DR InterPro; IPR018129; PEP_COase_Lys_AS.
DR InterPro; IPR033129; PEPCASE_His_AS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR PANTHER; PTHR30523:SF6; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR Pfam; PF00311; PEPcase; 1.
DR PRINTS; PR00150; PEPCARBXLASE.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 2.
DR PROSITE; PS00781; PEPCASE_1; 1.
DR PROSITE; PS00393; PEPCASE_2; 1.
PE 3: Inferred from homology;
KW Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300, ECO:0000256|HAMAP-
KW Rule:MF_00595};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_00595};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|HAMAP-Rule:MF_00595};
KW Pyruvate {ECO:0000313|EMBL:EGJ30408.1}.
FT REGION 110..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 217
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT ECO:0000256|PROSITE-ProRule:PRU10111"
FT ACT_SITE 719
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT ECO:0000256|PROSITE-ProRule:PRU10112"
SQ SEQUENCE 1072 AA; 122236 MW; 588E92FB091E5989 CRC64;
MSFLPSPSNQ DSTFPATSDL FLRHRLKIVE DLWESVLLSE CGQELVDLLK QLRELCSPEG
QATEDPKSSV ADLIQQLDLN EAIRASRAFA LYFQLINIVE QHYEQRNQQL SRRRSYRKST
EPELSPFSQG ILTKNGNSSF STVVTVEQEV DIGNDVTQPG GAVTNVIEKS QQENQGSQRK
LGLLDWLFPH LHKQNVPPGQ IQRLIDNLDI RLVFTAHPTE IVRRTIRGKQ RRMAKILEQL
DQAEQTYGTL GITSSWEVTE CSQKLMEEIR LWWRTDELHQ FKPGVLDEVD YTLHYFQEVL
FDTIPQLYSR FKQALKGSFP WLNPPAKNFC HFGSWVGSDR DGNPFVTPQI TWQTACYQRD
LVLGKYIGEV RNLTELLSLS LHWCDVLPEL LDSLEQDRSQ LPEVYEQLAI RYRQEPYRLK
LTYVKQKLEN TRERNQQLAN GMPVPDEMAN GKSWSFYRSG EEFLAELKLI ESNLLETGLN
CRELDNLICQ VEIYGFYLAH LDIRQESSRH SEALSEIAEY LQVLPKPYNL LSESEASLWL
TAELRTRRPL IPTELPFSEK TCETIETFRM VRQLQQEFGP QICQTYIISM SHTASDLLEV
LLLAKEAGLY DPATGKSTIR VVPLFETVED LKRAPAVMKS LFELPLYRAS LAGGYQQMQV
SPNNRQLNNL PYSNAKAEQP NNPDLKAVGH AARTATLREQ GLTSPNLQEV MLGYSDSNKD
SGFLSSNWEI HKAQKALEHM AEEYGIVLRI FHGRGGSVGR GGGPSYEAIL AQPGRSINGR
IKITEQGEVL ASRYSLPGLA LYHLETIATA VMQASLLNNG FDDIQPWNEI MEELAQISRS
HYRALIHDQP DLVDFFHQVT PIQEISQLQI SSRPARRKSG KKDLSSLRAI PWVFSWTQSR
FLLPSWYGVG TALQSFVDQA PEENINLLRC FYSKWPFFKM VISKVEMTLA KVDLQIAHHY
VKELSNPEDL ERFEHLFEQI AKEFNLTRNL VLTITGHQTL LDGDPNLQRS VHLRNGTIVP
LGFLQVSLLK RLRQHSNQVT LGVVQSRYSK GELLRGALLT INGIAAGMRN TG
//
