ID   F4Y5N4_KLEOX            Unreviewed;       198 AA.
AC   F4Y5N4;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE            EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
DE   Flags: Fragment;
GN   Name=blaOXY {ECO:0000313|EMBL:ADK32709.1};
OS   Klebsiella oxytoca.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=571 {ECO:0000313|EMBL:ADK32709.1};
RN   [1] {ECO:0000313|EMBL:ADK32709.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=36C {ECO:0000313|EMBL:ADK32709.1};
RA   Amador P., Fernandes R., Brito L., Prudencio C.;
RT   "ANTIBIOTIC RESISTANCE IN ENTEROBACTERIACEAE ISOLATED FROM PORTUGUESE DELI
RT   MEATS.";
RL   J. Food Saf. 31:1-20(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC         Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC         ChEBI:CHEBI:140347; EC=3.5.2.6;
CC         Evidence={ECO:0000256|ARBA:ARBA00001526};
CC   -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC       {ECO:0000256|ARBA:ARBA00009009}.
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DR   EMBL; GQ433980; ADK32709.1; -; Genomic_DNA.
DR   AlphaFoldDB; F4Y5N4; -.
DR   MEROPS; S11.A01; -.
DR   GO; GO:0008800; F:beta-lactamase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR045155; Beta-lactam_cat.
DR   InterPro; IPR000871; Beta-lactam_class-A.
DR   PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR   PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13354; Beta-lactamase2; 1.
DR   PRINTS; PR00118; BLACTAMASEA.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE   3: Inferred from homology;
KW   Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251}.
FT   DOMAIN          2..194
FT                   /note="Beta-lactamase class A catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF13354"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ADK32709.1"
FT   NON_TER         198
FT                   /evidence="ECO:0000313|EMBL:ADK32709.1"
SQ   SEQUENCE   198 AA;  21251 MW;  D8158C665CF85D60 CRC64;
     MCSTSKVMAA AAVLKQSESN KEVVNKRLEI NAADLVVWSP ITEKHLQSGM TLAELSAATL
     QYSDNTAMNL IIGYLGGPEK VTAFARSIGD ATFRLDRTEP TLNTAIPGDE RDTSTPLAMA
     ESLRKLTLGN ALGEQQRAQL VTWLKGNTTG GQSIRAGLPE SWVVGDKTGA GDYGTTNDIA
     VIWPENHAPL ILVTYFTQ
//