ID   F5AJ60_HELAN            Unreviewed;        78 AA.
AC   F5AJ60;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=cysteine dioxygenase {ECO:0000256|ARBA:ARBA00013133};
DE            EC=1.13.11.20 {ECO:0000256|ARBA:ARBA00013133};
DE   Flags: Fragment;
OS   Helianthus annuus (Common sunflower).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC   Heliantheae alliance; Heliantheae; Helianthus.
OX   NCBI_TaxID=4232 {ECO:0000313|EMBL:AEB37668.1};
RN   [1] {ECO:0000313|EMBL:AEB37668.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=50a {ECO:0000313|EMBL:AEB37668.1}, and 50b
RC   {ECO:0000313|EMBL:AEB37669.1};
RX   PubMed=20952500; DOI=10.1093/molbev/msq270;
RA   Strasburg J.L., Kane N.C., Raduski A.R., Bonin A., Michelmore R.,
RA   Rieseberg L.H.;
RT   "Effective population size is positively correlated with levels of adaptive
RT   divergence among annual sunflowers.";
RL   Mol. Biol. Evol. 28:1569-1580(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-cysteine + O2 = 3-sulfino-L-alanine + H(+);
CC         Xref=Rhea:RHEA:20441, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379,
CC         ChEBI:CHEBI:35235, ChEBI:CHEBI:61085; EC=1.13.11.20;
CC         Evidence={ECO:0000256|ARBA:ARBA00024284};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:20442;
CC         Evidence={ECO:0000256|ARBA:ARBA00024284};
CC   -!- COFACTOR:
CC       Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC         Evidence={ECO:0000256|ARBA:ARBA00001954};
CC   -!- SIMILARITY: Belongs to the cysteine dioxygenase family.
CC       {ECO:0000256|ARBA:ARBA00006622}.
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DR   EMBL; HQ431481; AEB37668.1; -; Genomic_DNA.
DR   EMBL; HQ431482; AEB37669.1; -; Genomic_DNA.
DR   AlphaFoldDB; F5AJ60; -.
DR   EnsemblPlants; mRNA:HanXRQr2_Chr13g0583431; mRNA:HanXRQr2_Chr13g0583431; HanXRQr2_Chr13g0583431.
DR   Gramene; mRNA:HanXRQr2_Chr13g0583431; mRNA:HanXRQr2_Chr13g0583431; HanXRQr2_Chr13g0583431.
DR   GO; GO:0017172; F:cysteine dioxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0070483; P:detection of hypoxia; IEA:UniProt.
DR   InterPro; IPR012864; PCO/ADO.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   PANTHER; PTHR22966:SF54; CYSTEINE DIOXYGENASE; 1.
DR   PANTHER; PTHR22966; UNCHARACTERIZED; 1.
DR   Pfam; PF07847; PCO_ADO; 1.
DR   SUPFAM; SSF51182; RmlC-like cupins; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AEB37668.1"
FT   NON_TER         78
FT                   /evidence="ECO:0000313|EMBL:AEB37668.1"
SQ   SEQUENCE   78 AA;  8643 MW;  6BA07ECEBE66110D CRC64;
     NFLLYALLLP ENAVIPLHDH PEMTVFSKLL VGKVHIKSYD LVNPDVIDNP PPSSQLKLAC
     LKEDGIFTAP CKTSVLYP
//