ID F5AR46_AERHY Unreviewed; 307 AA.
AC F5AR46;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=DNA gyrase subunit B {ECO:0000256|ARBA:ARBA00019166};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
GN Name=gyrB {ECO:0000313|EMBL:AEE38806.1};
OS Aeromonas hydrophila.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=644 {ECO:0000313|EMBL:AEE38806.1};
RN [1] {ECO:0000313|EMBL:AEE38806.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CECT 839 {ECO:0000313|EMBL:AEE38810.1}, MDC 231
RC {ECO:0000313|EMBL:AEE38811.1}, MDC 240 {ECO:0000313|EMBL:AEE38808.1},
RC MDC 2475 {ECO:0000313|EMBL:AEE38807.1}, MDC 27
RC {ECO:0000313|EMBL:AEE38809.1}, and MDC 48
RC {ECO:0000313|EMBL:AEE38806.1};
RX PubMed=21353754; DOI=10.1016/j.syapm.2010.11.014;
RA Martinez-Murcia A.J., Monera A., Saavedra M.J., Oncina R.,
RA Lopez-Alvarez M., Lara E., Figueras M.J.;
RT "Multilocus phylogenetic analysis of the genus Aeromonas.";
RL Syst. Appl. Microbiol. 34:189-199(2011).
RN [2] {ECO:0000313|EMBL:CCJ47326.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=140p {ECO:0000313|EMBL:CCJ47328.1}, 830
RC {ECO:0000313|EMBL:CCJ47329.1}, and D100 {ECO:0000313|EMBL:CCJ47326.1};
RA Beaz-Hidalgo R., Martinez-Murcia A., Figueras M.;
RT "Reclassification of Aeromonas hydrophila subsp. dhakensis Huys et al. 2002
RT as the medically important species Aeromonas aquariorum Martinez-Murcia et
RT al. 2008.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:BAO03462.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Ae11 {ECO:0000313|EMBL:BAO03469.1}, Ae34
RC {ECO:0000313|EMBL:BAO03492.1}, Ae4 {ECO:0000313|EMBL:BAO03462.1}, and
RC Ae45 {ECO:0000313|EMBL:BAO03503.1};
RA Jagoda S.S.S.D.S., Wijewardana T.G., Arulkanthan A., Igarashi Y.,
RA Engkong T., Kinoshita S., Asakawa S., Watabe S.;
RT "Characterization, antimicrobial susceptibility and virulence determinants
RT of motile Aeromonads isolated from septicaemic fresh water ornamental fish
RT in Sri Lanka: Predominance of Aeromonas veronii among diverse species.";
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
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DR EMBL; HQ442742; AEE38806.1; -; Genomic_DNA.
DR EMBL; HQ442743; AEE38807.1; -; Genomic_DNA.
DR EMBL; HQ442744; AEE38808.1; -; Genomic_DNA.
DR EMBL; HQ442745; AEE38809.1; -; Genomic_DNA.
DR EMBL; HQ442746; AEE38810.1; -; Genomic_DNA.
DR EMBL; HQ442747; AEE38811.1; -; Genomic_DNA.
DR EMBL; AB829115; BAO03462.1; -; Genomic_DNA.
DR EMBL; AB829122; BAO03469.1; -; Genomic_DNA.
DR EMBL; AB829145; BAO03492.1; -; Genomic_DNA.
DR EMBL; AB829156; BAO03503.1; -; Genomic_DNA.
DR EMBL; HE965665; CCJ47326.1; -; Genomic_DNA.
DR EMBL; HE965667; CCJ47328.1; -; Genomic_DNA.
DR EMBL; HE965668; CCJ47329.1; -; Genomic_DNA.
DR AlphaFoldDB; F5AR46; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00822; TopoII_Trans_DNA_gyrase; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.670; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR001241; Topo_IIA.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR000565; Topo_IIA_B.
DR InterPro; IPR013759; Topo_IIA_B_C.
DR InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR InterPro; IPR018522; TopoIIA_CS.
DR InterPro; IPR006171; TOPRIM_domain.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF00204; DNA_gyraseB; 1.
DR Pfam; PF01751; Toprim; 1.
DR PRINTS; PR01159; DNAGYRASEB.
DR SMART; SM00433; TOP2c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR PROSITE; PS00177; TOPOISOMERASE_II; 1.
DR PROSITE; PS50880; TOPRIM; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 269..307
FT /note="Toprim"
FT /evidence="ECO:0000259|PROSITE:PS50880"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEE38806.1"
FT NON_TER 307
FT /evidence="ECO:0000313|EMBL:AEE38806.1"
SQ SEQUENCE 307 AA; 33857 MW; AF6975B6666F6ECF CRC64;
EPQAPLKQIG DSTGTGTEVR FWPSPTIFSD TLFHYEILAK RLRELSFLNS GVSIRLLDER
DGREAHFCYE GGIKAFVEYL NQNKTPIHPK VFHFTTEQDG IGVEVAMQWN DAYQEGVYCF
TNNIPQRDGG THLVGFRTAL TRTLNSYMDK EDYSKKAKSA ASGDDVREGL IAVISVKVPD
PKFSSQTKDK LVSSEVKTAV EQAMGEKLAD FLLENPGDAK IVVNKIIDAA RAREAARKAR
ELTRRKGALD IAGLPGKLAD CQEKDPALSE LYIVEGDSAG GSAKQGRNRK NQAILPLKGK
ILNVEKA
//
