ID   F5NXZ3_SHIFL            Unreviewed;       163 AA.
AC   F5NXZ3;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=Uracil permease domain protein {ECO:0000313|EMBL:EGK35441.1};
GN   ORFNames=SFK227_3120 {ECO:0000313|EMBL:EGK35441.1};
OS   Shigella flexneri K-227.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=766147 {ECO:0000313|EMBL:EGK35441.1, ECO:0000313|Proteomes:UP000004520};
RN   [1] {ECO:0000313|EMBL:EGK35441.1, ECO:0000313|Proteomes:UP000004520}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K-227 {ECO:0000313|EMBL:EGK35441.1,
RC   ECO:0000313|Proteomes:UP000004520};
RA   Rasko D., Redman J., Daugherty S.C., Tallon L., Sadzewicz L., Jones K.,
RA   Santana-Cruz I., Liu X.;
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGK35441.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AFGY01000042; EGK35441.1; -; Genomic_DNA.
DR   AlphaFoldDB; F5NXZ3; -.
DR   PATRIC; fig|766147.3.peg.3078; -.
DR   Proteomes; UP000004520; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   InterPro; IPR006042; Xan_ur_permease.
DR   PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        100..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        125..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   163 AA;  16856 MW;  A735E5A0BE8570AF CRC64;
     MFANGLSTVI SGFFGSTPNT TYGENIGVMA ITRVYSTWVI GGAAIFAILL SCVGKLAAAI
     QMIPLPVMGG VSLLLYGVIG ASGIRVLIES KVDYNKAQNL ILTSVILIIG VSGAKVNIGA
     AELKGMALAT IVGIGLSLIF KLISVLRPEE VVLDAEDADI TDK
//