ID F5RAF2_METUF Unreviewed; 1168 AA.
AC F5RAF2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Chromosome partition protein Smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN Name=smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN ORFNames=METUNv1_01313 {ECO:0000313|EMBL:EGK72548.1};
OS Methyloversatilis universalis (strain ATCC BAA-1314 / JCM 13912 / FAM5).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Sterolibacteriaceae; Methyloversatilis.
OX NCBI_TaxID=1000565 {ECO:0000313|EMBL:EGK72548.1, ECO:0000313|Proteomes:UP000005019};
RN [1] {ECO:0000313|EMBL:EGK72548.1, ECO:0000313|Proteomes:UP000005019}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1314 / JCM 13912 / FAM5
RC {ECO:0000313|Proteomes:UP000005019};
RX PubMed=21725020; DOI=10.1128/JB.05331-11;
RA Kittichotirat W., Good N.M., Hall R., Bringel F., Lajus A., Medigue C.,
RA Smalley N.E., Beck D., Bumgarner R., Vuilleumier S., Kalyuzhnaya M.G.;
RT "Genome sequence of Methyloversatilis universalis FAM5T, a methylotrophic
RT representative of the order Rhodocyclales.";
RL J. Bacteriol. 193:4541-4542(2011).
CC -!- FUNCTION: Required for chromosome condensation and partitioning.
CC {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC each terminus and a third globular domain forming a flexible hinge near
CC the middle of the molecule. These domains are separated by coiled-coil
CC structures. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGK72548.1}.
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DR EMBL; AFHG01000036; EGK72548.1; -; Genomic_DNA.
DR RefSeq; WP_008060005.1; NZ_AFHG01000036.1.
DR AlphaFoldDB; F5RAF2; -.
DR STRING; 1000565.METUNv1_01313; -.
DR eggNOG; COG1196; Bacteria.
DR OrthoDB; 9808768at2; -.
DR Proteomes; UP000005019; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd03278; ABC_SMC_barmotin; 2.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01894; Smc_prok; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR011890; SMC_prok.
DR NCBIfam; TIGR02168; SMC_prok_B; 1.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Coiled coil {ECO:0000256|HAMAP-Rule:MF_01894};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01894};
KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Reference proteome {ECO:0000313|Proteomes:UP000005019}.
FT DOMAIN 3..1148
FT /note="RecF/RecN/SMC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02463"
FT DOMAIN 522..617
FT /note="SMC hinge"
FT /evidence="ECO:0000259|Pfam:PF06470"
FT COILED 170..197
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 286..341
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 370..397
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 437..478
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 663..697
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 740..767
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 986..1013
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT BINDING 32..39
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
SQ SEQUENCE 1168 AA; 129023 MW; 13869DDD76EB2F7A CRC64;
MRLSKLKLAG FKTFVDPTTI QMPGQLVGVV GPNGCGKSNI IDAVRWVLGE SRASALRGDA
MTDVIFNGSG TRKPVGRASV ELVFDNAQGR AAGQWSQYAE IAVKRVLERD GQSDYYINNT
RVRRRDVIDV FLGTGLGPRA YAIIEQGMIT RIIEARPEEL RAFLEEAAGI TKYRERRKET
QGRLDDARDN LVRLDDIVGE LGSRIDRLQK QAEVAARYTE LNRRLSERQA LLWALKQRAA
AAEAETLAQD AGRLENDIER DTAALRHHEA ALERIRTEHF ASSEAVHAAQ AELLTANAEA
SRLEDDLKRA AENRHKLQAR IAQLEGEVAN WRARIEGIET DIGRWTELAD HAAHRIEQAE
ARHETTSALL PEAEAAFQEA EQQASVARRE LAAVEQQLKV EETHRANAGR TLNSLAGRRE
RIAHDEAQLV EPDREALALA QDKLESLQMA QEAAQQRLHA AQNAVPQLQA QVRNAQDAER
AATRTLTETR ARRDALVELQ RKTQSDGKLA PWLAALGLQD AKPLWQSLQV DAGWEMAVEA
VLRERLGALE VPDADTLARA RAAGAAPQNL TLALPGQDAS AAVPADSLRH RVRAQDARWN
ALLDLWLGPV AAVESLDGTA TGPRVDREGR LAHGASLTLY APDARTHGVL ERARDIEGLG
AEIDEADVRL AESREMLREA EAALAGAHEE QAAARREQQS LTQAAHSAQV EQIKLAQAVS
RFDEQKAALA RDRAEVELAE QTEQAHLERA DAEIERAREL IEVQRMRLDS ALDAQKNADI
QLREARFADQ AAVRELQEAN FSQRECSSRL TDLGNNLGMA KTQLENAELE RALRSDEFAQ
IDEGSIDARL QQVLDNRRAR EQVLATCRDA QEVLAAQLRD LESQRANTEH TLAPARERLA
DLKLRQQAAL LNAEQYAQRL AEIELPEGRL DALVAEGEAE KVKEGALNGE IGRLGREIAA
LGAVNLAALE ELAQASERKG YLDAQSTDLR DAIATLEDAI RRMDRETRAL LKETYDRVNA
EFGRIFPELF GGGEARLVMT GEEILDAGLQ VFAQPPGKRN ASIQLLSGGE KALTATALVF
AFFQLNPAPF CMLDEVDAPL DDTNTERFCE MVKRMSASTQ FVFISHNKIT MEMAQQLVGV
TMQERGCSRV VEVDMEAALK LRDEALSV
//
