ID   F5RB35_METUF            Unreviewed;       217 AA.
AC   F5RB35;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   24-JAN-2024, entry version 40.
DE   SubName: Full=Histidine biosynthesis protein {ECO:0000313|EMBL:EGK72171.1};
GN   ORFNames=METUNv1_01474 {ECO:0000313|EMBL:EGK72171.1};
OS   Methyloversatilis universalis (strain ATCC BAA-1314 / JCM 13912 / FAM5).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Sterolibacteriaceae; Methyloversatilis.
OX   NCBI_TaxID=1000565 {ECO:0000313|EMBL:EGK72171.1, ECO:0000313|Proteomes:UP000005019};
RN   [1] {ECO:0000313|EMBL:EGK72171.1, ECO:0000313|Proteomes:UP000005019}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1314 / JCM 13912 / FAM5
RC   {ECO:0000313|Proteomes:UP000005019};
RX   PubMed=21725020; DOI=10.1128/JB.05331-11;
RA   Kittichotirat W., Good N.M., Hall R., Bringel F., Lajus A., Medigue C.,
RA   Smalley N.E., Beck D., Bumgarner R., Vuilleumier S., Kalyuzhnaya M.G.;
RT   "Genome sequence of Methyloversatilis universalis FAM5T, a methylotrophic
RT   representative of the order Rhodocyclales.";
RL   J. Bacteriol. 193:4541-4542(2011).
CC   -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC   -!- SIMILARITY: Belongs to the HisA/HisF family.
CC       {ECO:0000256|ARBA:ARBA00009667, ECO:0000256|RuleBase:RU003657}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGK72171.1}.
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DR   EMBL; AFHG01000042; EGK72171.1; -; Genomic_DNA.
DR   AlphaFoldDB; F5RB35; -.
DR   STRING; 1000565.METUNv1_01474; -.
DR   eggNOG; COG1411; Bacteria.
DR   Proteomes; UP000005019; Unassembled WGS sequence.
DR   GO; GO:0003949; F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity; IEA:InterPro.
DR   GO; GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006062; His_biosynth.
DR   InterPro; IPR044524; Isoase_HisA-like.
DR   InterPro; IPR011060; RibuloseP-bd_barrel.
DR   PANTHER; PTHR43090; 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE; 1.
DR   PANTHER; PTHR43090:SF2; 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE; 1.
DR   Pfam; PF00977; His_biosynth; 1.
DR   SUPFAM; SSF51366; Ribulose-phoshate binding barrel; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605,
KW   ECO:0000256|RuleBase:RU003657};
KW   Histidine biosynthesis {ECO:0000256|ARBA:ARBA00023102,
KW   ECO:0000256|RuleBase:RU003657};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005019}.
SQ   SEQUENCE   217 AA;  22048 MW;  1AC94C118F5132AA CRC64;
     MIDLMQGQVV HARRGDRQAY QPLRSRLVEG CAPEAVVDAL IAATGAGHLY IADLDAIRGL
     GDHRAQIAAL VARHPAIEFW VDGGFAGAAA ARALHAATGA LPILGSETLT EPAALATLAA
     TGVPALLSLD HRGGLPLGPA WAHDATGWPA RVIAMELARV GADSGPDLAL IARLRALRPQ
     VSVIAAGGVR DAADLAALDA AGVPAVLVAS ALHDGRL
//