ID F5RJQ5_9FIRM Unreviewed; 346 AA.
AC F5RJQ5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=L-iditol 2-dehydrogenase {ECO:0000313|EMBL:EGK61564.1};
DE EC=1.1.1.14 {ECO:0000313|EMBL:EGK61564.1};
GN Name=gutB {ECO:0000313|EMBL:EGK61564.1};
GN ORFNames=HMPREF9081_0490 {ECO:0000313|EMBL:EGK61564.1};
OS Centipeda periodontii DSM 2778.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Selenomonadaceae;
OC Centipeda.
OX NCBI_TaxID=888060 {ECO:0000313|EMBL:EGK61564.1, ECO:0000313|Proteomes:UP000004067};
RN [1] {ECO:0000313|EMBL:EGK61564.1, ECO:0000313|Proteomes:UP000004067}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2778 {ECO:0000313|EMBL:EGK61564.1,
RC ECO:0000313|Proteomes:UP000004067};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGK61564.1}.
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DR EMBL; AFHQ01000015; EGK61564.1; -; Genomic_DNA.
DR RefSeq; WP_006305331.1; NZ_GL892076.1.
DR AlphaFoldDB; F5RJQ5; -.
DR STRING; 888060.HMPREF9081_0490; -.
DR eggNOG; COG1063; Bacteria.
DR HOGENOM; CLU_026673_11_0_9; -.
DR OrthoDB; 1674659at2; -.
DR Proteomes; UP000004067; Unassembled WGS sequence.
DR GO; GO:0003939; F:L-iditol 2-dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd08261; Zn_ADH7; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR PANTHER; PTHR43401:SF2; L-THREONINE 3-DEHYDROGENASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EGK61564.1}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 7..340
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 346 AA; 37354 MW; 0B9D53E3F5125523 CRC64;
MKGIRINQPG EAEIFETEKP VRKAGEALLR VLYGGICGSD LGTYRGTFAY ASYPRIPGHE
FSAQIVAIDP ADAEKYHLHA GQIITCNPYF NCGTCYSCTR GFVNCCEHNE TMGAQRDGAF
TEYITMPVER IYDGKGLSPL QLALIEPFCI SYHGASHADI KPGEKVLVIG AGTIGVLAAA
AAKAAGAEVY IADIAPKKLD HAVQIMGLAG RILNDSPEHF TEQVQEITGG NGFDVTIEAV
GLPATFLSCV DAAAFGGRVV QVGVGKRNAD FNFTLLQKKE LKLYGSRNAL KKDFLELIDL
VKSGKIDITK IVTNTYELAD GPQAFKDFSE HADTMLKVVI HFADPE
//
