ID F5RKT2_9FIRM Unreviewed; 343 AA.
AC F5RKT2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=D-3-phosphoglycerate dehydrogenase {ECO:0000313|EMBL:EGK60877.1};
DE EC=1.1.1.95 {ECO:0000313|EMBL:EGK60877.1};
GN Name=serA3 {ECO:0000313|EMBL:EGK60877.1};
GN ORFNames=HMPREF9081_0879 {ECO:0000313|EMBL:EGK60877.1};
OS Centipeda periodontii DSM 2778.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Selenomonadaceae;
OC Centipeda.
OX NCBI_TaxID=888060 {ECO:0000313|EMBL:EGK60877.1, ECO:0000313|Proteomes:UP000004067};
RN [1] {ECO:0000313|EMBL:EGK60877.1, ECO:0000313|Proteomes:UP000004067}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2778 {ECO:0000313|EMBL:EGK60877.1,
RC ECO:0000313|Proteomes:UP000004067};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00005854,
CC ECO:0000256|RuleBase:RU003719}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGK60877.1}.
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DR EMBL; AFHQ01000026; EGK60877.1; -; Genomic_DNA.
DR RefSeq; WP_006305762.1; NZ_GL892076.1.
DR AlphaFoldDB; F5RKT2; -.
DR STRING; 888060.HMPREF9081_0879; -.
DR eggNOG; COG1052; Bacteria.
DR HOGENOM; CLU_019796_1_3_9; -.
DR OrthoDB; 9805416at2; -.
DR Proteomes; UP000004067; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd12171; 2-Hacid_dh_10; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029752; D-isomer_DH_CS1.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42789; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090); 1.
DR PANTHER; PTHR42789:SF1; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090); 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003719}.
FT DOMAIN 61..132
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 133..308
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 343 AA; 37841 MW; 287677B952EE6826 CRC64;
MKLIGIGDLL IPARYIEEGF AGYRQKGVQI EVLDWPLKDY EELQGINLQV ETQGSEVYDV
PDALIKKLRD AEILITQFCP ITKKVLDACT KLRFIGVLRG GYENVNVTYA AQKGVTVYHT
PGRNATAVAD FTIGMILSEC RNIARAHANL KAGRWVRDYV NAATVPDLED KTVGIIGMGQ
IGRKVAKRLH GFDVRILGYD PYADTLPDYV VRASLDELLE QADFVTIHGR LTDETKGMMN
AHAFSLMKPT AYFINTARAG LVDEAALYAA LKERRIQGAA LDVFEHEPLK EDDPLVGLDN
VTITPHLAGG TVDAFLHSPV LLAREMEGAL SGDLTSRCIV RQK
//
