ID   F5TA52_9FIRM            Unreviewed;       592 AA.
AC   F5TA52;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Creatinase {ECO:0000313|EMBL:EGL38863.1};
GN   ORFNames=HMPREF9126_0024 {ECO:0000313|EMBL:EGL38863.1};
OS   Parvimonas sp. oral taxon 110 str. F0139.
OC   Bacteria; Bacillota; Tissierellia; Tissierellales; Peptoniphilaceae;
OC   Parvimonas.
OX   NCBI_TaxID=767100 {ECO:0000313|EMBL:EGL38863.1, ECO:0000313|Proteomes:UP000003475};
RN   [1] {ECO:0000313|EMBL:EGL38863.1, ECO:0000313|Proteomes:UP000003475}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0139 {ECO:0000313|EMBL:EGL38863.1,
RC   ECO:0000313|Proteomes:UP000003475};
RA   Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA   Nelson K.E.;
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M24B family.
CC       {ECO:0000256|ARBA:ARBA00008766}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGL38863.1}.
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DR   EMBL; AFII01000001; EGL38863.1; -; Genomic_DNA.
DR   AlphaFoldDB; F5TA52; -.
DR   STRING; 767100.HMPREF9126_0024; -.
DR   OrthoDB; 9806388at2; -.
DR   Proteomes; UP000003475; Unassembled WGS sequence.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   CDD; cd01085; APP; 1.
DR   Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR   Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR   InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR   InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR   InterPro; IPR000587; Creatinase_N.
DR   InterPro; IPR000994; Pept_M24.
DR   InterPro; IPR033740; Pept_M24B.
DR   InterPro; IPR032416; Peptidase_M24_C.
DR   PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR   PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR   Pfam; PF01321; Creatinase_N; 1.
DR   Pfam; PF16189; Creatinase_N_2; 1.
DR   Pfam; PF00557; Peptidase_M24; 1.
DR   Pfam; PF16188; Peptidase_M24_C; 1.
DR   SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR   SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 2.
PE   3: Inferred from homology;
FT   DOMAIN          5..135
FT                   /note="Creatinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01321"
FT   DOMAIN          312..522
FT                   /note="Peptidase M24"
FT                   /evidence="ECO:0000259|Pfam:PF00557"
FT   DOMAIN          532..592
FT                   /note="Peptidase M24 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16188"
SQ   SEQUENCE   592 AA;  67014 MW;  D5F9E986171B82BC CRC64;
     MINERISKLR KLMAKRNIDA YIVPSSDPHQ SEYLADYYKT REFITGFTGS AGTAVITTKK
     SGLWTDGRYF IQAAKELAVG EVELYKIGVP DSISIEEFLL KEFPSRGAKI AFDGNNTSVA
     EYENLMKKLP NFEFITDVDY VGDIWNEEGR PAKPDSKVYI FDEKYSGEST SNRIARLREM
     MKEKGIDYHF IGSLDDIAYV LNIRANDVQC NPVVISYLLV SENACNLYID KSKLSEEVAN
     YLKENNISIK AYEVIGRDIS DIEAKKTLYL ETKKTNVAVY SSIGRGVNVV TGLNLTSIMK
     CHKNEIEIKN TKNAFIKDGV ALVRYLNWLE TGVSTGTITE MIASEKLFEF RKQQDLFIED
     SFEAISAYGA NASMPHYKPS HEHPVKVEPR GLYLIDSGGH YLDGTTDITR TVALGELKEE
     EIYHYTLVLK AHIALMEAKF LEGTNGGYLD AFTRYNLWKN RINFNHGTGH GVGHVLNVHE
     GPQRIGTAGN EYPMEVGMIT SDEPGIYISG SHGIRIESIM VCVKDEMTEF GQFLKFDNLT
     VVPIDTRPVD KSLMSEEEIT WLNDYNKMCY EKLSPYLSGH DLEYLREQCK EI
//