ID   F5X257_STRPX            Unreviewed;       739 AA.
AC   F5X257;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   SubName: Full=Polar amino acid transport system permease/substrate-binding protein {ECO:0000313|EMBL:BAK30366.1};
GN   OrderedLocusNames=SGPB_1319 {ECO:0000313|EMBL:BAK30366.1};
OS   Streptococcus pasteurianus (strain ATCC 43144 / JCM 5346 / CDC 1723-81).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=981540 {ECO:0000313|EMBL:BAK30366.1, ECO:0000313|Proteomes:UP000007946};
RN   [1] {ECO:0000313|EMBL:BAK30366.1, ECO:0000313|Proteomes:UP000007946}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43144 / JCM 5346 / CDC 1723-81
RC   {ECO:0000313|Proteomes:UP000007946};
RX   PubMed=21633709; DOI=10.1371/journal.pone.0020519;
RA   Lin I.-H., Liu T.-T., Teng Y.-T., Wu H.-L., Liu Y.-M., Wu K.-M.,
RA   Chang C.-H., Hsu M.-T.;
RT   "Sequencing and comparative genome analysis of two pathogenic Streptococcus
RT   gallolyticus subspecies: genome plasticity, adaptation and virulence.";
RL   PLoS ONE 6:E20519-E20519(2011).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. {ECO:0000256|RuleBase:RU363032}.
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DR   EMBL; AP012054; BAK30366.1; -; Genomic_DNA.
DR   RefSeq; WP_013852035.1; NC_015600.1.
DR   AlphaFoldDB; F5X257; -.
DR   STRING; 981540.SGPB_1319; -.
DR   KEGG; stb:SGPB_1319; -.
DR   HOGENOM; CLU_019602_20_0_9; -.
DR   Proteomes; UP000007946; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0071705; P:nitrogen compound transport; IEA:InterPro.
DR   CDD; cd13619; PBP2_GlnP; 1.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; MetI-like; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 4.
DR   InterPro; IPR010065; AA_ABC_transptr_permease_3TM.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   InterPro; IPR001638; Solute-binding_3/MltF_N.
DR   NCBIfam; TIGR01726; HEQRo_perm_3TM; 1.
DR   PANTHER; PTHR35936:SF17; GLUTAMINE-BINDING PERIPLASMIC PROTEIN; 1.
DR   PANTHER; PTHR35936; MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F; 1.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   Pfam; PF00497; SBP_bac_3; 2.
DR   SMART; SM00062; PBPb; 2.
DR   SMART; SM00079; PBPe; 1.
DR   SUPFAM; SSF161098; MetI-like; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 2.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007946};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363032};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363032};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363032}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..739
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5038396380"
FT   TRANSMEM        540..562
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        574..595
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        712..731
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   DOMAIN          536..731
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS50928"
SQ   SEQUENCE   739 AA;  80078 MW;  5264A0681DD28F94 CRC64;
     MKHKLKALML AIFSVFFVFG VKAQADTISI VSDTAYAPFE FKDSDQTYKG IDVDIIKEVA
     KREGWDYEQT YPGFDAAVNA VQAGQADALM AGTTVTDARK KVFTFSDTYY DTSIVIYTKS
     GNTAISKYSQ LKGKTVGVKN GTAAQTWLDE HADKYGYTVK TFDTSDLMNN SLDSGSIDAA
     MDDTPVVQYA INQGKSYEIN IDAESIGSFA FAVKKGSSYE YLIDEFNEAL AAMKEDGTYD
     QIMQKWLGDS YTSSSTSSSS NSSAASSTLT LTGDASAKAT PVKSTYKIVM DSSFAPFEYQ
     NDSGEYEGID VELIKAIAEQ QGFNVEISNP GFDAALNAVQ AGQADAVIAG MSITDARKEI
     FDFSDAYYTS NILLAVKSGS SVKSYSDLKG LTVGAKNGTS SYTWLSEHAD EYGYTLKAFD
     EASTMYDSLN SGSIDALMDD EAVLLYAIQQ GRDFETPIAG EKSGEYGFAV SKGSNPELIE
     MFNNGLAALV ESGEYDEIVN KYLDTSDSSS SSSSTVDETT IWGLLKNNYS QLLAGLGKTL
     SLTLISFAIA MVIGIIFGMM AVAPNKVLRT ISAVFVDIVR GIPLMIVAAF IFWGIPNLLE
     SITGRQSPIN DFVAATIALS LNGGAYIAEI VRGGIEAVPQ GQMEASRSLG ISYGKTMQKI
     ILPQAIRLML PNFINQFVIS LKDTTIVSAI GLVELFQTGK IIIARNYQSF RVYAILAVIY
     LVMITLLTRL AKRLEKRLK
//