ID F5X4N9_STRPX Unreviewed; 190 AA.
AC F5X4N9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Probable DNA-directed RNA polymerase subunit delta {ECO:0000256|HAMAP-Rule:MF_00357};
DE AltName: Full=RNAP delta factor {ECO:0000256|HAMAP-Rule:MF_00357};
GN Name=rpoE {ECO:0000256|HAMAP-Rule:MF_00357,
GN ECO:0000313|EMBL:BAK29379.1};
GN OrderedLocusNames=SGPB_0245 {ECO:0000313|EMBL:BAK29379.1};
OS Streptococcus pasteurianus (strain ATCC 43144 / JCM 5346 / CDC 1723-81).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=981540 {ECO:0000313|EMBL:BAK29379.1, ECO:0000313|Proteomes:UP000007946};
RN [1] {ECO:0000313|EMBL:BAK29379.1, ECO:0000313|Proteomes:UP000007946}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43144 / JCM 5346 / CDC 1723-81
RC {ECO:0000313|Proteomes:UP000007946};
RX PubMed=21633709; DOI=10.1371/journal.pone.0020519;
RA Lin I.-H., Liu T.-T., Teng Y.-T., Wu H.-L., Liu Y.-M., Wu K.-M.,
RA Chang C.-H., Hsu M.-T.;
RT "Sequencing and comparative genome analysis of two pathogenic Streptococcus
RT gallolyticus subspecies: genome plasticity, adaptation and virulence.";
RL PLoS ONE 6:E20519-E20519(2011).
CC -!- FUNCTION: Participates in both the initiation and recycling phases of
CC transcription. In the presence of the delta subunit, RNAP displays an
CC increased specificity of transcription, a decreased affinity for
CC nucleic acids, and an increased efficiency of RNA synthesis because of
CC enhanced recycling. {ECO:0000256|HAMAP-Rule:MF_00357}.
CC -!- SUBUNIT: RNAP is composed of a core of 2 alpha, a beta and a beta'
CC subunits. The core is associated with a delta subunit and one of
CC several sigma factors. {ECO:0000256|HAMAP-Rule:MF_00357}.
CC -!- SIMILARITY: Belongs to the RpoE family. {ECO:0000256|ARBA:ARBA00009828,
CC ECO:0000256|HAMAP-Rule:MF_00357}.
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DR EMBL; AP012054; BAK29379.1; -; Genomic_DNA.
DR RefSeq; WP_003063238.1; NC_015600.1.
DR AlphaFoldDB; F5X4N9; -.
DR STRING; 981540.SGPB_0245; -.
DR GeneID; 76469277; -.
DR KEGG; stb:SGPB_0245; -.
DR HOGENOM; CLU_116648_0_0_9; -.
DR Proteomes; UP000007946; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.1250; RNA polymerase, subunit delta, N-terminal domain; 1.
DR HAMAP; MF_00357; RNApol_bact_RpoE; 1.
DR InterPro; IPR007759; Asxl_HARE-HTH.
DR InterPro; IPR038087; RNAP_delta_N_dom_sf.
DR InterPro; IPR029757; RpoE.
DR NCBIfam; TIGR04567; RNAP_delt_lowGC; 1.
DR Pfam; PF05066; HARE-HTH; 1.
DR PROSITE; PS51913; HTH_HARE; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|HAMAP-Rule:MF_00357};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695, ECO:0000256|HAMAP-
KW Rule:MF_00357}; Reference proteome {ECO:0000313|Proteomes:UP000007946};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00357};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|HAMAP-
KW Rule:MF_00357}.
FT DOMAIN 14..83
FT /note="HTH HARE-type"
FT /evidence="ECO:0000259|PROSITE:PS51913"
FT REGION 100..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..190
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 190 AA; 22074 MW; F274C9C5B882086E CRC64;
MELEVFAGQE KSELSMIEVA RAILEERGRD HEMYFSDLVN EIQNYLEKSD AEIREALPYF
YSALNVDGSF IPLGDNKWGL RSWYAIDEID EEIITLEEDE NGAPKRKPKR VNAFMDGDED
AIDYSDDDPE DEDFTPESSD LEYDEENPDD EKSEVESYDS EINEIIPDED LDEEVDINEE
DDEDDDLDEE
//
