ID   F6CTD7_MARPP            Unreviewed;       804 AA.
AC   F6CTD7;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:AEF53986.1};
GN   OrderedLocusNames=Mar181_0937 {ECO:0000313|EMBL:AEF53986.1};
OS   Marinomonas posidonica (strain CECT 7376 / NCIMB 14433 / IVIA-Po-181).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Oceanospirillaceae; Marinomonas.
OX   NCBI_TaxID=491952 {ECO:0000313|EMBL:AEF53986.1, ECO:0000313|Proteomes:UP000009230};
RN   [1] {ECO:0000313|EMBL:AEF53986.1, ECO:0000313|Proteomes:UP000009230}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 7376 / NCIMB 14433 / IVIA-Po-181
RC   {ECO:0000313|Proteomes:UP000009230};
RX   PubMed=23458837; DOI=10.4056/sigs.2976373;
RA   Lucas-Elio P., Goodwin L., Woyke T., Pitluck S., Nolan M., Kyrpides N.C.,
RA   Detter J.C., Copeland A., Lu M., Bruce D., Detter C., Tapia R., Han S.,
RA   Land M.L., Ivanova N., Mikhailova N., Johnston A.W., Sanchez-Amat A.;
RT   "Complete genome sequence of Marinomonas posidonica type strain (IVIA-Po-
RT   181(T)).";
RL   Stand. Genomic Sci. 7:31-43(2012).
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DR   EMBL; CP002771; AEF53986.1; -; Genomic_DNA.
DR   RefSeq; WP_013795462.1; NC_015559.1.
DR   AlphaFoldDB; F6CTD7; -.
DR   STRING; 491952.Mar181_0937; -.
DR   KEGG; mpc:Mar181_0937; -.
DR   eggNOG; COG5001; Bacteria.
DR   eggNOG; COG5002; Bacteria.
DR   HOGENOM; CLU_000445_70_46_6; -.
DR   OrthoDB; 9804951at2; -.
DR   Proteomes; UP000009230; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00989; PAS; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        160..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          395..533
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          542..797
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   804 AA;  90999 MW;  A084C561F6B34C12 CRC64;
     MSLVFSKSLI VKQALLTLVL AVVLSLISNA IQMYDGIKHQ RKIIDQDFNE LIAVVEQPLA
     AAVFRLDRAF AQQQINSLLL SPSIASVKVT DEIGHIFIEG KAEKRAFRSS VALADLMFSN
     LNTFQRSLTI EQPTFNAGIL TVVPEKRYLM DRLLDTHIPL LVYNLLKDIL LACLISLIFY
     YLVTYPLMRF TRSLTHIGQH QKQPLPDAFY QRHKSDELGH LHTTFTQLWT HLNSALSDLE
     RSNSHTKAMI EHAADGILLL DVNQQIRMAN SAAKTMLKLE QNDVTSVSLA RFHDPLHWPE
     FVNLVDTLSL NSPQTVETLY QVQGRQFPVE IRLVKYDVQD QVETLMLIRN VSERKEAEAH
     IHHLAYYDPI TDLPNRQYLT DRLTERLKLT AMQNSYSAVV FMDLDRFKVI NDSLGHNVGD
     QLLRCVSKQL AGLVSSEVVF ARMGGDEFAF LLEPLGDHLA EAEQRVLDLM NRITLACQQV
     KSAGHHEVHI TASLGASVFQ ANDLCAEVIL KQADTALYRA KESGRNTYAM YRPEMQAASD
     ARLEMEKALH HATENKLFEL YYQPQNNAEG ELIGAEALLR WRDSNKGFIS PAEFIPLAEE
     IGLIVEIGTW VLNEALSQVA TWLEQGKWQS SWRMSINVSP IQFQQASFLP ILKSQLEKHH
     VPASCVDLEI TENTLLNDWE TSLTKMQAIK ELGVYLSIDD FGTGYSSLKY LKSLPIDRLK
     IDQSFVRDLL TDHSDEAIVH AVIAMAKALK INVLAEGVET LPHLDRLKEI HCFYYQGYYF
     GRPAPADQFI ASFVHDSSDT APSF
//