ID F6D448_METPW Unreviewed; 477 AA.
AC F6D448;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Mur ligase middle domain protein {ECO:0000313|EMBL:AEG17470.1};
GN OrderedLocusNames=MSWAN_0430 {ECO:0000313|EMBL:AEG17470.1};
OS Methanobacterium paludis (strain DSM 25820 / JCM 18151 / SWAN1).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobacterium.
OX NCBI_TaxID=868131 {ECO:0000313|EMBL:AEG17470.1, ECO:0000313|Proteomes:UP000009231};
RN [1] {ECO:0000313|Proteomes:UP000009231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25820 / JCM 18151 / SWAN1
RC {ECO:0000313|Proteomes:UP000009231};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Chertkov O., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Pagani I., Cadillo-Quiroz H.,
RA Imachi H., Zinder S., Liu W., Woyke T.;
RT "Complete sequence of Methanobacterium sp. SWAN-1.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEG17470.1, ECO:0000313|Proteomes:UP000009231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25820 / JCM 18151 / SWAN1
RC {ECO:0000313|Proteomes:UP000009231};
RX PubMed=24449792; DOI=10.1099/ijs.0.059964-0;
RA Cadillo-Quiroz H., Brauer S.L., Goodson N., Yavitt J.B., Zinder S.H.;
RT "Methanobacterium paludis sp. nov. and a novel strain of Methanobacterium
RT lacus isolated from northern peatlands.";
RL Int. J. Syst. Evol. Microbiol. 64:1473-1480(2014).
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DR EMBL; CP002772; AEG17470.1; -; Genomic_DNA.
DR RefSeq; WP_013824972.1; NC_015574.1.
DR AlphaFoldDB; F6D448; -.
DR STRING; 868131.MSWAN_0430; -.
DR GeneID; 10667914; -.
DR KEGG; mew:MSWAN_0430; -.
DR eggNOG; arCOG02820; Archaea.
DR HOGENOM; CLU_022291_4_2_2; -.
DR OrthoDB; 75177at2157; -.
DR Proteomes; UP000009231; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:InterPro.
DR Gene3D; 3.90.190.20; Mur ligase, C-terminal domain; 1.
DR Gene3D; 3.40.1190.10; Mur-like, catalytic domain; 1.
DR InterPro; IPR018109; Folylpolyglutamate_synth_CS.
DR InterPro; IPR036565; Mur-like_cat_sf.
DR InterPro; IPR004101; Mur_ligase_C.
DR InterPro; IPR036615; Mur_ligase_C_dom_sf.
DR InterPro; IPR013221; Mur_ligase_cen.
DR PANTHER; PTHR23135:SF7; LIPID II ISOGLUTAMINYL SYNTHASE (GLUTAMINE-HYDROLYZING) SUBUNIT MURT; 1.
DR PANTHER; PTHR23135; MUR LIGASE FAMILY MEMBER; 1.
DR Pfam; PF02875; Mur_ligase_C; 1.
DR Pfam; PF08245; Mur_ligase_M; 1.
DR SUPFAM; SSF53623; MurD-like peptide ligases, catalytic domain; 1.
DR SUPFAM; SSF53244; MurD-like peptide ligases, peptide-binding domain; 1.
DR PROSITE; PS01011; FOLYLPOLYGLU_SYNT_1; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:AEG17470.1}.
FT DOMAIN 111..303
FT /note="Mur ligase central"
FT /evidence="ECO:0000259|Pfam:PF08245"
FT DOMAIN 326..368
FT /note="Mur ligase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02875"
SQ SEQUENCE 477 AA; 52153 MW; C933A520E6AC5747 CRC64;
MDIIKTSYLA DKVNGKLIGP DKEISGIFNF LNTSKRGDAV IRHWIDEKGV EIAVSKGVSC
IITQNPQGNA IETAKKLKFP LIITEKIELA NAFAISWAVE NFATDSIRIV VTGTNGKSTT
THMIYSILKE AGYNTYTNTD SKSEFNTLID PIVSKQIAEF PDKIEAMVVE VSEVQGWLGK
LMKNHASLMT SAIDPNVVVL TNVALDHIGL VNSVEEAFDE ISGSIKALKK PKKTIAVLNH
DDPLIRKMEN FKGNDTEVIF YGEGAAVESK AEGIFYEGKL LIKKEDLPFK SQHFIQNTMA
AIEASLSLNV DLKYIKSAVT SYKPLKRRFN ILSQNPLIID DFAHNPNGIV VTINSAAKIT
KGKLCLVTAI RGSRGDPINL ANAEAIVKGL KGLEKGTNFN LIITTSTDFV DKANVVKNSE
KDVFLNTLEK EGLSYIFHET LHNALKAALK SAGKEDTILL IGAQGMDPAS DVLRSID
//
