ID F6DAM7_THICA Unreviewed; 466 AA.
AC F6DAM7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Trk system potassium uptake protein TrkA {ECO:0000256|ARBA:ARBA00017378};
GN OrderedLocusNames=Thicy_1525 {ECO:0000313|EMBL:AEG32283.1};
OS Thiomicrospira cyclica (strain DSM 14477 / JCM 11371 / ALM1)
OS (Thioalkalimicrobium cyclicum).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Thiomicrospira.
OX NCBI_TaxID=717773 {ECO:0000313|EMBL:AEG32283.1, ECO:0000313|Proteomes:UP000009232};
RN [1] {ECO:0000313|EMBL:AEG32283.1, ECO:0000313|Proteomes:UP000009232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14477 / JCM 11371 / ALM1
RC {ECO:0000313|Proteomes:UP000009232};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Davenport K., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Pagani I., Kappler U., Woyke T.;
RT "Complete sequence of Thioalkalimicrobium cyclicum ALM1.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002776; AEG32283.1; -; Genomic_DNA.
DR RefSeq; WP_013836058.1; NC_015581.1.
DR AlphaFoldDB; F6DAM7; -.
DR STRING; 717773.Thicy_1525; -.
DR KEGG; tcy:Thicy_1525; -.
DR eggNOG; COG0569; Bacteria.
DR HOGENOM; CLU_046525_0_2_6; -.
DR OrthoDB; 9775180at2; -.
DR Proteomes; UP000009232; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR006036; K_uptake_TrkA.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR Pfam; PF02254; TrkA_N; 2.
DR PRINTS; PR00335; KUPTAKETRKA.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
DR PROSITE; PS51201; RCK_N; 2.
PE 4: Predicted;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000009232};
KW Transport {ECO:0000256|ARBA:ARBA00023065}.
FT DOMAIN 2..129
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 146..232
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 239..361
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 373..458
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 466 AA; 52211 MW; 153DB947FD4E359A CRC64;
MNIIILGAGQ VGSSLAELLV TDDNDITLVD LDNSHLQRLQ DRLDIRTIHG HASHPDILIQ
AGLETADLLI AATQNDETNI CACQIAHILQ KSVTKIARVR GNSYLEHAEL FDKTLNDNAI
PIDVLISPEG LVTNYILQLI AYPGSLQVID FADGRVRLVA MRAHNGGPLV GKKISELKHH
LPSRLRFRIV AIYRHDEVVM PTGDVTIRVG DEVFFMAEPH DISQIVEEFR REKQKRARNI
MIAGGGHIGF NLAKQLENSH QVKIIEHNIT RAREIAEVLD RAIIINGDVA DKDLLIEENI
DEIDLFIAVT NQDEANIISS MLAKKLGVKR VIALVNNQSY LDLIHLNSID IAISADRITT
NNLLHYMRKG DTVKAFTLRR GTAEAMEVIV HGSENSSKII GKRLIDVDWP QDITIGCIIR
DNEVMLAHRD LVIEAEDHVI LFLTDRSRTQ QIAELFSPEQ KRGWLR
//
